Results 71 to 80 of about 13,113,594 (336)

Experimental methods for studying amyloid cross‐interactions

open access: yesProtein Science
AbstractInteractions between amyloid proteins represent the cornerstone of various pathogenic pathways, including prion conversion and co‐development of distinct kinds of systemic amyloidosis. Various experimental methodologies provide insights into the effects of such cross‐interactions on amyloid self‐assembly, which range from acceleration to ...
Aleksandra Kalitnik   +12 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The cross-spectrum experimental method

open access: yes, 2010
40 pages, table of symbols, 19 figures, 30 references.
Rubiola, Enrico, Vernotte, Francois
openaire   +2 more sources

Experimental study of crossing angle collision [PDF]

open access: yesProceedings of International Conference on Particle Accelerators, 2002
The non-linear coupling due to the beam-beam interaction with crossing angle has been studied. The major effect of a small (/spl sim/12 mrad) crossing angle is to excite 5Q/sub xspl plusmn/Q/sub s/ integer coupling resonance family on large amplitude particles, which results in bad lifetime, On the CESR, a small crossing angle (/spl sim/2.4 mr) was ...
Chen, T.   +4 more
openaire   +1 more source

Appendix B. Experimental crosses generated and the number of families generated per cross.

open access: yes, 2016
Experimental crosses generated and the number of families generated per ...
Patrick O'Reilly (2906444)   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The effect of hybrid transgression on environmental tolerance in experimental yeast crosses

open access: yesJournal of Evolutionary Biology, 2014
Evidence is rapidly accumulating that hybridization generates adaptive variation. Transgressive segregation in hybrids could promote the colonization of new environments.
R. Stelkens   +4 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Generation mean analysis for grain yield and its components in popcorn

open access: yesOpen Agriculture, 2018
Knowledge about genetic composition of a character helps plant breeders to plan their breeding programs. Grain yield and related traits are very important in maize breeding programs.
Fahad Shah   +11 more
doaj   +1 more source

Generating Fiber Crossing Phantoms Out of Experimental DWIs [PDF]

open access: yes, 2007
In Diffusion Tensor Imaging (DTI), differently oriented fiber bundles inside one voxel are incorrectly modeled by a single tensor. High Angular Resolution Diffusion Imaging (HARDI) aims at using more complex models, such as a two-tensor model, for estimating two fiber bundles.
Caan, Matthan   +6 more
openaire   +3 more sources

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