Results 81 to 90 of about 13,113,594 (336)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BLOCKING IN PARTIAL DIALLEL CROSSES
Generally the parents are included in the experimental material for combining ability analysis for comparing the performance of crosses with parents and also for calculating heterosis.
D. R. Aneja +3 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The phenomenon of fluctuating chili prices can be resolved in stages, one of which is through multiple crosses. However, this cross requires precise methods in the evaluation and selection process, especially regarding fruit characteristics.
Muhammad Fuad Anshori +10 more
doaj +1 more source
The present investigation was carried out at Research Farm of Tirhut College of Agriculture, Dholi, Muzaffarpur, Bihar. The experimental material consisted of three genotypes of resistant mungbean and urdbean donor each viz., HUM-16, TMB-37, Samrat and ...
Sima Sinha, S. B. Mishra, Alok Kumar and S.S. Pandey
doaj +1 more source
Influence of the male ejaculate on post-mating prezygotic barriers in field crickets. [PDF]
Post-copulatory interactions between males and females involve highly coordinated, complex traits that are often rapidly evolving and divergent between species.
Erica L Larson +2 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
MORPHOLOGICAL IDENTIFICATION OF SOME WHEAT VARIETIES AND ITS CROSSES. [PDF]
The field experiments were conducted out during 2013/2014 and 2014/2015 seasons at the Experimental Station Farm of Agronomy Department, Faculty of Agriculture, Mansoura University, Dakahlia Governorate, Egypt to evaluate the morphological (quantitative ...
A. Alfahdawey +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source

