Results 81 to 90 of about 13,113,594 (336)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

BLOCKING IN PARTIAL DIALLEL CROSSES

open access: yes, 1998
Generally the parents are included in the experimental material for combining ability analysis for comparing the performance of crosses with parents and also for calculating heterosis.
D. R. Aneja   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Multivariate analysis and image-based phenotyping of cayenne fruit traits in selection and diversity mapping of multiple F1 cross lines

open access: yesReproduction and Breeding
The phenomenon of fluctuating chili prices can be resolved in stages, one of which is through multiple crosses. However, this cross requires precise methods in the evaluation and selection process, especially regarding fruit characteristics.
Muhammad Fuad Anshori   +10 more
doaj   +1 more source

Estimation of gene effects for yield attributing traits in mungbean (Vigna radiata) and urdbean (Vigna mungo) for intra and interspecific crosses

open access: yesElectronic Journal of Plant Breeding, 2020
The present investigation was carried out at Research Farm of Tirhut College of Agriculture, Dholi, Muzaffarpur, Bihar. The experimental material consisted of three genotypes of resistant mungbean and urdbean donor each viz., HUM-16, TMB-37, Samrat and ...
Sima Sinha, S. B. Mishra, Alok Kumar and S.S. Pandey
doaj   +1 more source

Influence of the male ejaculate on post-mating prezygotic barriers in field crickets. [PDF]

open access: yesPLoS ONE, 2012
Post-copulatory interactions between males and females involve highly coordinated, complex traits that are often rapidly evolving and divergent between species.
Erica L Larson   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

MORPHOLOGICAL IDENTIFICATION OF SOME WHEAT VARIETIES AND ITS CROSSES. [PDF]

open access: yesJournal of Plant Production, 2015
The field experiments were conducted out during 2013/2014 and 2014/2015 seasons at the Experimental Station Farm of Agronomy Department, Faculty of Agriculture, Mansoura University, Dakahlia Governorate, Egypt to evaluate the morphological (quantitative ...
A. Alfahdawey   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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