Results 1 to 10 of about 3,726,731 (344)

Agronomic and Physiological Traits, and Associated Quantitative Trait Loci (QTL) Affecting Yield Response in Wheat (Triticum aestivum L.): A Review

Frontiers in Plant Science, 2019
Enhanced grain yield has been achieved in bread wheat (Triticum aestivum L.) through development and cultivation of superior genotypes incorporating yield-related agronomic and physiological traits derived from genetically diverse and complementary ...
Nkhathutsheleni Maureen Tshikunde, J. Mashilo, H. Shimelis, A. Odindo   +3 more
semanticscholar   +1 more source

Marker-Assisted Introgression of Quantitative Trait Loci [PDF]

Genetics, 1997
The use of molecular markers for the introgression of one or several superior QTL alleles into a recipient line is investigated using analytic and simulation results. The positions of the markers devoted to the control of the genotype at the QTLs in a “foreground selection” step are optimized given the confidence interval of the QTL position.
Hospital, Frederic, Charcosset, Alain
openaire   +3 more sources

Massively parallel reporter assay confirms regulatory potential of hQTLs and reveals important variants in lupus and other autoimmune diseases

HGG Advances
Summary: We designed a massively parallel reporter assay (MPRA) in an Epstein-Barr virus transformed B cell line to directly characterize the potential for histone post-translational modifications, i.e., histone quantitative trait loci (hQTLs ...
Yao Fu, Jennifer A. Kelly, Jaanam Gopalakrishnan, Richard C. Pelikan, Kandice L. Tessneer, Satish Pasula, Kiely Grundahl, David A. Murphy, Patrick M. Gaffney   +8 more
doaj   +1 more source

Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice

Journal of Lipid Research, 2011
To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analysis between inbred mouse strains MRL/MpJ and SM/J, measuring triglyceride levels at 8 weeks of age in F2 mice fed a chow diet.
Magalie S. Leduc, Rachael S. Hageman, Ricardo A. Verdugo, Shirng-Wern Tsaih, Kenneth Walsh, Gary A. Churchill, Beverly Paigen   +6 more
doaj   +1 more source

Quantitative trait loci from identification to exploitation for crop improvement

Plant Cell Reports, 2017
Advancement in the field of genetics and genomics after the discovery of Mendel’s laws of inheritance has led to map the genes controlling qualitative and quantitative traits in crop plant species.
J. Kumar, D. S. Gupta, Sunanda Gupta, S. Dubey, Priyanka Gupta, Shiv Kumar   +5 more
semanticscholar   +1 more source

Mapping epistatic quantitative trait loci

BMC Genetics, 2014
How to map quantitative trait loci (QTL) with epistasis efficiently and reliably has been a persistent problem for QTL mapping analysis. There are a number of difficulties for studying epistatic QTL. Linkage can impose a significant challenge for finding epistatic QTL reliably. If multiple QTL are in linkage and have interactions, searching for QTL can
Laurie, Cecelia, Wang, Shengchu, Carlini-Garcia, Luciana Aparecida, Zeng, Zhao-Bang   +3 more
openaire   +2 more sources

Linkage disequilibrium interval mapping of quantitative trait loci

BMC Genomics, 2006
Background For many years gene mapping studies have been performed through linkage analyses based on pedigree data. Recently, linkage disequilibrium methods based on unrelated individuals have been advocated as powerful tools to refine estimates of gene ...
de Rochambeau Hubert, Abdallah Jihad, Boitard Simon, Cierco-Ayrolles Christine, Mangin Brigitte   +4 more
doaj   +1 more source

Construction of a high-density genetic map by specific locus amplified fragment sequencing (SLAF-seq) and its application to Quantitative Trait Loci (QTL) analysis for boll weight in upland cotton (Gossypium hirsutum.)

BMC Plant Biology, 2016
Upland Cotton (Gossypium hirsutum) is one of the most important worldwide crops it provides natural high-quality fiber for the industrial production and everyday use.
Zhen Zhang, Haihong Shang, Yuzhen Shi, Long Huang, Junwen Li, Qun Ge, Juwu Gong, Aiying Liu, Tingting Chen, Dan Wang, Yan-Ling Wang, Koffi Kibalou Palanga, Jamshed Muhammad, Weijie Li, Quanwei Lu, Xiaoying Deng, Yunna Tan, Weiwu Song, Juan Cai, Pengtao Li, H. Rashid, Wan-Kui Gong, Youlu Yuan   +22 more
semanticscholar   +1 more source

Nonparametric Functional Mapping of Quantitative Trait Loci [PDF]

Biometrics, 2009
SummaryFunctional mapping is a useful tool for mapping quantitative trait loci (QTL) that control dynamic traits. It incorporates mathematical aspects of biological processes into the mixture model‐based likelihood setting for QTL mapping, thus increasing the power of QTL detection and the precision of parameter estimation.
Yang, Jie, Wu, Rongling, Casella, George
openaire   +3 more sources

Druggable genome-wide Mendelian randomization integrating GWAS and eQTL/pQTL data identifies targets for lung squamous cell carcinoma

Scientific Reports
Lung squamous cell carcinoma (LUSC) is one of the most common types of non-small cell lung cancer with poor prognosis. Druggable genome-wide Mendelian randomization (MR) was conducted to discover LUSC-related targets using expression quantitative trait ...
Shizhao Cheng, Hao Zhang, Zhenliang Shi, Daqiang Sun   +3 more
doaj   +1 more source