Results 1 to 10 of about 3,758,767 (255)
Quantitative Trait Loci for Murine Growth [PDF]
Genetics, 1996 Abstract Body size is an archetypal quantitative trait with variation due to the segregation of many gene loci, each of relatively minor effect, and the environment. We examine the effects of quantitative trait loci (QTLs) on age-specific body weights and growth in the F2 intercross of the LG/J and SM/J strains of inbred mice.
Cheverud J.M. +5 more
openaire +3 more sources
Quantitative Trait Loci: A Meta-analysis [PDF]
Genetics, 2000 Abstract This article presents a method to combine QTL results from different independent analyses. This method provides a modified Akaike criterion that can be used to decide how many QTL are actually represented by the QTL detected in different experiments. This criterion is computed to choose between models with one, two, three, etc.,
Goffinet, Bruno, Gerber, Sophie
openaire +3 more sources
Quantitative trait loci and metabolic pathways [PDF]
Proceedings of the National Academy of Sciences, 1998 The interpretation of quantitative trait locus (QTL) studies is limited by the lack of information on metabolic pathways leading to most economic traits. Inferences about the roles of the underlying genes with a pathway or the nature of their interaction with other loci are generally not possible.
M D, McMullen +6 more
openaire +2 more sources
Mapping quantitative trait loci for behavioral traits in the mouse [PDF]
Behavior Genetics, 1992 After many years of studying various behavioral characters in the mouse, it is clear that most are heritable and are specified by complexes of genes or quantitative trait loci (QTLs). In order to attain a more complete understanding of the genetic causes of individual differences in behavior, the mechanism of action of these QTLs must be elucidated ...
T E, Johnson, J C, DeFries, P D, Markel
openaire +2 more sources
Quantitative Trait Loci for Biofortification Traits in Maize Grain [PDF]
Journal of Heredity, 2011 Detecting genes that influence biofortification traits in cereal grain could help increase the concentrations of bioavailable mineral elements in crops to solve the global mineral malnutrition problem. The aims of this study were to detect the quantitative trait loci (QTLs) for phosphorus (P), iron (Fe), zinc (Zn), and magnesium (Mg) concentrations in ...
Šimić, Domagoj +7 more
openaire +4 more sources
Bayesian Quantitative Trait Loci Mapping for Multiple Traits [PDF]
Genetics, 2008 AbstractMost quantitative trait loci (QTL) mapping experiments typically collect phenotypic data on multiple correlated complex traits. However, there is a lack of a comprehensive genomewide mapping strategy for correlated traits in the literature. We develop Bayesian multiple-QTL mapping methods for correlated continuous traits using two multivariate ...
Samprit, Banerjee +2 more
openaire +2 more sources
Bayes factors for detection of Quantitative Trait Loci [PDF]
Genetics Selection Evolution, 2001 A fundamental issue in quantitative trait locus (QTL) mapping is to determine the plausibility of the presence of a QTL at a given genome location. Bayesian analysis offers an attractive way of testing alternative models (here, QTL vs. no-QTL) via the Bayes factor. There have been several numerical approaches to computing the Bayes factor, mostly based
Varona Aguado, Luís +2 more
openaire +4 more sources
Marker-Assisted Introgression of Quantitative Trait Loci [PDF]
Genetics, 1997 The use of molecular markers for the introgression of one or several superior QTL alleles into a recipient line is investigated using analytic and simulation results. The positions of the markers devoted to the control of the genotype at the QTLs in a “foreground selection” step are optimized given the confidence interval of the QTL position.
Hospital, Frederic, Charcosset, Alain
openaire +3 more sources
Mapping epistatic quantitative trait loci
BMC Genetics, 2014 How to map quantitative trait loci (QTL) with epistasis efficiently and reliably has been a persistent problem for QTL mapping analysis. There are a number of difficulties for studying epistatic QTL. Linkage can impose a significant challenge for finding epistatic QTL reliably. If multiple QTL are in linkage and have interactions, searching for QTL can
Laurie, Cecelia +3 more
openaire +2 more sources
Nonparametric Functional Mapping of Quantitative Trait Loci [PDF]
Biometrics, 2009 SummaryFunctional mapping is a useful tool for mapping quantitative trait loci (QTL) that control dynamic traits. It incorporates mathematical aspects of biological processes into the mixture model‐based likelihood setting for QTL mapping, thus increasing the power of QTL detection and the precision of parameter estimation.
Yang, Jie, Wu, Rongling, Casella, George
openaire +3 more sources