Results 41 to 50 of about 109,986 (307)

Quantitative Trait Loci Affecting Milk Production Traits in Finnish Ayrshire Dairy Cattle

, 2003
A whole genome scan of Finnish Ayrshire was conducted tomap quantitative trait loci (QTL) affecting milk production. The analysis included 12 half-sib families containing a total of 494 bulls in a granddaughter design.
Virta, J, Virta, A, Kinos, R., Virta, A., Viitala, Sirja M., Viitala, S.M., de Koning, D. J., Vilkki, J H, Mäki-Tanila, Asko, Viitala, S M, Mäki-Tanila, A, Schulman, N F, Kinos, R, Vilkki, J. H., Schulman, Nina F., Elo, Kari, Viitala, S. M., Elo, K, Kinos, Riikka, Koning, D.J., de, Vilkki, Johanna, de Koning, D J, de Koning, Dirk-Jan, Virta, Anneli, Elo, K., Schulman, N. F., Virta, J., Schulman, N.F., Vilkki, J.H., Virta, Jouni, Mäki-Tanila, A., de Koning, D.J.   +31 more
core   +1 more source

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. [PDF]

, 2014
Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality.
Paternoster, Lavinia, Byrne, E.M. (Enda), Wolffenbuttel, B.H.R. (Bruce H. R.), Wolffenbuttel, Bruce H. R., Yerges-Armstrong, L.M. (Laura), Pylkaes, Katri, Ridker, P.M., Knight, Julia A., Marek Zygmunt, Ingelsson, E., Michael J. Econs, Anton-Culver, H., Sanna, Serena, Murray, A, Storniolo, A.M., McCarthy, Mark I, Boerwinkle, E., Snieder, Harold; id_orcid, Anneli Pouta, Corre, T, Ganna, A, Gudbjartsson, D.F. (Daniel), Amin, N. (Najaf), García-Closas, M, Bolla, Manjeet K, Mangino, M., Kosma, V.M., Bandinelli, S, Econs, M.J. (Michael), Beckmann, Matthias W., Koller, DL, Rudolph, A. (Anja), Sanna, S., Heli Nevanlinna, Rose, LM, Uitterlinden, Andre G., Andrew C. Heath, David Karasik, Smith, AV, Schmidt, Marjanka K., Couch, F.J. (Fergus), Coviello, A.D., Alizadeh, Behrooz Z., Chang Claude, Jenny, Per Hall, Paolo Peterlongo, Uitterlinden, André G, Streeten, Elizabeth A., Perry, J.R., Zoltan Kutalik, Bonanni, Bernardo, Lambrechts, D., John P. Rice, Järvelin, MR, Hopper, JL, Kutalik, Zoltan, Davey Smith, George, Stefansson, K, Willemsen, G.A.H.M. (Gonneke), Czene, Kamila, McMahon, G, Lawlor, Debbie, Gasparini, P, Kosma, V-M, Pylkaes, K, de Geus, Eco E.J., Kjellqvist, Sanela, Dennis, J. (Joe), Rose, Lynda M, Timpson, Nicholas J, Montgomery, G.W., Gisli Masson, Hofman, A., Bierut, L.J., Harris, T.B. (Tamara), Smith, Albert V, Wolffenbuttel, Bruce Hr, Melanie Waldenberger, Lunetta, KL, Douglas F. Easton, Milani, L., Veli-Matti Kosma, Study, AOC, Day, Felix, Nohr, EA, Johnson, A.D. (Andrew), Davey Smith, G., de Geus, E.J., Econs, MJ, Rose, L.M. (Lynda), Paternoster, L., Pylkäs, Katri, Smith, GD, Rivadeneira, F, Benítez, J. (Javier), Ulivi, S. (Shelia), Anton-Culver, H. (Hoda), Murabito, J. (Joanne), Pharoah, P.D., Hooning, MJ, Bojesen, S.E., Lindblom, A., Lavinia Paternoster, Strachan, David P., Salomaa, Veikko, Ong, KK, Lude Franke, Smith, G., Alizadeh, B.Z., Tune H. Pers, Ingelsson, Erik, Craig E. Pennell, Garcia-Closas, M., Econs, M.J., Järvelin, M.-R., Stöckl, Doris, Andres Metspalu, Stampfer, M.J. (Meir J.), Kyriaki Michailidou, Ulivi, S, Ellen W. Demerath, et al., Andrew D. Johnson, Heath, AndrewC., McCarthy, MI, Foroud, Tatiana, Milne, R.L., Hopper, J.L., Cox, A, Franceschini, N. (Nora), García Closas, Montserrat, Schlessinger, D. (David), Bojesen, Stig E., Nolte, Ilja M, Sorensen, TIA, Garcia, Melissa E., Koller, D.L., Völzke, H. (Henry), Milne, Roger L, Peterlongo, Paolo, de Geus, EE, Pers, TH, Brauch, H, Pharoah, P.D.P., Mannermaa, A. (Arto), Franceschini, N, Martin, Nicholas G, Melbye, Mads, de Geus, E.E., Chasman, Daniel I., Cox, Angela, Yerges-Armstrong, Laura M., Wright, MJ, Fernando Rivadeneira, Magnusson, Patrik K., Evelin Mihailov, Gieger, C. (Christian), Yerges Armstrong, Laura M., George Davey Smith, Sørensen, T.I.A., Marjanka K. Schmidt, Stampfer, Meir J., Erin K. Wagner, Ong, K.K., Nicholas G. Martin, Wareham, N.J., Nicholas J. Timpson, McArdle, Patrick F., Winqvist, Robert, Mangino, M, Streeten, Elizabeth A, Guo, S. (Suiqun), Giles, GG, Tsernikova, N. (Natalia), Pennell, Craig E, Robino, A, Hermann Brenner, Nicholas J. Wareham, Chen, J. (Jinhui), Loos, Ruth J. F., Pedersen, Nancy L., Thompson, DJ, Heath, A.C., Johan G. Eriksson, Järvelin, Marjo-Riitta, Hall, Per, Lindblom, Annika, Murabito, Joanne M., Stolk, L., Hunter, DJ, Rice, John P., Annika Lindblom, Nolte, I.M. (Ilja), Pedersen, Nancy L, Duijn, C.M. van, De Vivo, Immaculata, Loos, RJF, Feenstra, B. (Bjarke), Vivo, I. De, Nolte, Ilja M.; id_orcid, Bolla, M.K. (Manjeet), Franke, L, Völzke, H, Wright, M.J. (Margaret), Feenstra, Bjarke, Dunning, A.M. (Alison), Brauch, H., Lambrechts, Diether, Australian Ovarian Canc Study, Bojesen, SE, Mads Melbye, Hamann, U. (Ute), Wallaschofski, Henri, Paternoster, L. (Lavinia), Hottenga, JJ (Jouke Jan), Ang, W.Q., Haring, R. (Robin), Hottenga, J.J., Hartman, Catharina A., Giles, Graham G, Demerath, EW, Cornelia M. van Duijn, Kiel, Douglas P, Stöckl, D., Peterlongo, P, Nancy L. Pedersen, Neven, P, Visser, Jenny, Wolffenbuttel, BHR, Hua Zhao, Jing, Milne, RL, Perry, J.R.B. (John), Beckmann, MW, Boyd, H.A. (Heather), Thorsteinsdottir, U, Magnusson, Patrik K, Snieder, H. (Harold), Sørensen, TI, Pedersen, N.L. (Nancy L.), Jing Hua Zhao, Salomaa, V. (Veikko), Blomqvist, Carl, van Duijn, Cornelia M., Behrooz Z. Alizadeh, Australian Ovarian Cancer Study, Pers, Tune H., McArdle, W.L. (Wendy), Milne, Roger L., Thorsteinsdottir, U. (Unnur), Eriksson, J.G., Brenner, H, Kiel, Douglas, Koller, Daniel L, Easton, Douglas F., Enda M. Byrne, Nohr, Ellen A, Kiel, D.P., Atsma, Femke, Eleonora Porcu, D’adamo, A.P., Collee, Margriet, Andrulis, I.L. (Irene), Ulivi, S., de Geus, EEJ, Waldenberger, M., Snieder, Harold, Giles, G.G., Murabito, J.M., Ferreira, T., Hooning, Maartje J, Flesch Janys, Dieter, Hagen, K. (Knut), Oldehinkel, Albertine J, Garcia, ME, Tim D. Spector, Peto, J., Melbye, M, Knight, J.A. (Julia), Zhao, JH, Nolte, IM, Pharoah, Paul D. P., Stig E. Bojesen, Oostra, Ben A, Michailidou, K, Blomqvist, C, Schlessinger, David, David J. Hunter, Douglas P. Kiel, Chenevix Trench, Georgia, Stampfer, Meir, Hu, Frank, Kathryn L. Lunetta, Ingelsson, E, Cousminer, Diana L, Vollenweider, P, Pouta, A. (Anneli), Econs, Michael J., Gudbjartsson, Daniel F., Lawlor, D, Widen, E. (Elisabeth), Ang, Wei Q., Kutalik, Z. (Zoltán), Esko, T. (Tõnu), Elisabeth Widen, Coveillo, Andrea D, Hartman, Catharina A, Geller, F., Melbye, M., Johnson, Andrew D., Zhao, J., McCarthy, M.I. (Mark), Geus, E.E.J. de, Eriksson, Johan G, Boyd, Heather A, Stolk, L. (Lisette), Duijn, C.M. (Cornelia) van, Anton Culver, Hoda, Wolffenbuttel, B.H.R., Hopper, John L., Streeten, E.A. (Elizabeth), Hamann, U, Najaf Amin, Mägi, R., Cousminer, Diana L., Mihailov, Evelin, Wang, Q. (Qing), Visser, J.A. (Jenny), Bierut, LJ, Collée, JM, Ring, S, Nolte, I.M., Brenner, H. (Hermann), Cox, A. (Angela), Geller, F. (Frank), Pykäs, K. (Katri), Benitez, Javier, Serena Sanna, Storniolo, A.M. (Anna M.), Munro Peacock, Doris Stöckl, Salomaa, V., Julie E. Buring, Chasman, D.I. (Daniel), Hunter, D.J., Tõnu Esko, Teumer, A. (Alexander), Aida K. Dieffenbach, Garcia, Melissa E, Johnson, A.D., Beckmann, Matthias W, Vollenweider, P., Waeber, G. (Gérard), Fasching, P.A., Early Growth Genetics EGG Consorti, Michailidou, K., Atsma, F, Gudbjartsson, Daniel F, Wang, Q, Wallaschofski, H. (Henri), Dunning, Alison M, Porcu, E., Bergmann, S, Day, F.R. (Felix), Albrecht, E. (Eva), Palotie, Aarno, Kari Stefansson, Bolla, Manjeet K., Neven, Patrick, Ang, Wei Q, Lunetta, Kathryn L, Khaw, KT, Hottenga, J.J. (Jouke Jan), Hamann, Ute, Hu, Frank B., Albert V. Smith, Kosma, Veli-Matti, Smith, A.V., Masson, Gisli, Pharoah, Paul Dp, David P. Strachan, Mihailov, E., Nora Franceschini, Dennis, Joe, Wareham, Nicholas J, Chasman, DI, Chen, Jinhui, Sovio, U. (Ulla), Masson, G., Eriksson, JG, Ellen A. Nohr, McArdle, Patrick F, Smith, G.D., Franceschini, N., Vilmundur Gudnason, Rudolph, Anja, Radice, Paolo, Visser, Jenny A, Natalia Tšernikova, Laura J. Bierut, Pedersen, N.L., Study, KLC, Haring, Robin, Heath, AndrewC, Chang-Claude, J, Milani, Lili, Murray, A., Jarvelin, M.-R. (Marjo-Riitta), Pedersen, NL, Bjarke Feenstra, Robert Winqvist, Storniolo, Anna M., Wolffenbuttel, B.H., Geus, E.E. de, Waeber, G., Hu, FB, Pouta, A., Widen, Elisabeth, Dieffenbach, A.K. (Aida Karina), Karasik, D. (David), Guo, SQ, Franke, Lude, He, Chunyan, Perry, JR, Peacock, M, Peterlongo, P. (Paolo), Ang, W.Q. (Wei), Carl Blomqvist, Pennell, Craig E., Hall, P., Järvelin, Marjo Riitta, Heath, A., Bojesen, Stig E, Porcu, E. (Eleonora), Sørensen, Thorkild Ia, Hooning, Maartje, Mark I. McCarthy, Wright, Margaret J, Joe Dennis, Boerwinkle, E.A. (Eric), Gerard Waeber, Guo, S., Perry, John R.B., Network, GENICA, Bergmann, S., Guénel, P, Thompson, D. (Deborah), Peto, J, Sulem, Patrick, Southey, Mellissa C., Murabito, JM, Frank Geller, Gudbjartsson, DF, Teumer, Alexander, Magnusson, P.K. (Patrik), Catharina A. Hartman, Chanock, Stephen, Paul D. P. Pharoah, Julian Peto, Heath, AC, Hooning, M.J. (Maartje), Ring, S., David Schlessinger, Bandinelli, S. (Stefania), Hottenga, JJ, Zygmunt, Marek, Stampfer, MJ, Pennell, CE, Wendy L. McArdle, He, CY, Peterlongo, P., Veikko Salomaa, Porcu, Eleonora, de Geus, E.J.C., Dorret I. Boomsma, Willemsen, G.; id_orcid, Henri Wallaschofski, Postma, Dirkje S, Khaw, Kay-Tee, Montgomery, Grant W, Byrne, EM, Coveillo, Andrea D., Devilee, P, Stampfer, M., Pouta, A, Feenstra, B., Amin, N, Stefansson, Kari, Ferreira, T. (Teresa), Gasparini, Paolo, Consortium, InterAct, Spector, T.D. (Timothy), Postma, D.S., Rose, L.M., Porcu, E, Nohr, E.A., Boomsma, Dorret I., Ganna, A., McArdle, W.L., Vollenweider, Peter, He, C. (Chunyan), Alizadeh, BZ, Arto Mannermaa, Kraft, Peter, He, C, Perry, JRB, Thompson, Deborah J, Schmidt, MK (Marjanka), Reedik Mägi, Felix Day, Hofman, A. (Albert), Zhao, J.H. (Jing Hua), Flyger, H., Albert Hofman, Geller, F, Nohr, C. (Christian), Voelzke, H, D'adamo, A.P., Foroud, T., Nevanlinna, H., Ganna, Andrea, Corre, T., Gieger, Christian, Buring, Julie E, Karasik, D., Peacock, Munro, Geus, E.J.C. (Eco) de, Esko, T., Aarno Palotie, Blomqvist, C. (Carl), Kosma, VM, Oldehinkel, AJ (A.), Oldehinkel, A.J., Palotie, A. (Aarno), Graham G. Giles, Loos, RJ, Katri Pylkäs, Peter A. Fasching, Czene, K., Hottenga, Jouke Jan, Bierut, Laura J., Jaervelin, Marjo-Riitta, Chanock, S.J. (Stephen), Franke, L., Thorleifsson, Gudmar, Study, Australian Ovarian Canc, Alexander Teumer, Amin, N., Hartman, C.A., Oostra, B.A., Couper, D.J. (David), Ring, Susan, Christian Gieger, Streeten, EA, Bierut, L.J. (Laura), Geller, Frank, Albrecht, E, Chunyan He, John R. B. Perry, Andrulis, IL, Peacock, M., Perry, John Rb, McMahon, George, Sanela Kjellqvist, McArdle, P.F., Oostra, Ben, Lynda M. Rose, Visser, Jenny; id_orcid, Paolo Gasparini, Patrick Neven, Hottenga, Jouke-Jan, Spector, T.D., Mannermaa, A, Loos, R.J.F., D’adamo, Adamo Pio, Yerges-Armstrong, Laura M, Heath, A, Waeber, G, Nevanlinna, H, Loos, R.J., Kosma, Veli Matti, Gasparini, P. (Paolo), Nevanlinna, H. (Heli), Winqvist, R., Ring, S.M. (Susan), Sørensen, T.I., Wolffenbuttel, BH, Lai, Sandra, Stolk, L, Sanna, S. (Serena), Widen, E, Couper, D., Postma, DS, Crisponi, L., Tatiana Foroud, Chasman, D.I., Easton, D.F., Chang-Claude, Jenny, Wagner, E.K. (Erin K.), He, C., Radice, P, Storniolo, Anna M, Chenevix-Trench, G., Heather A. Boyd, Khaw, Kay Tee, Jinhui Chen, Adamo, P. (Pio) d', Stoeckl, D, Brenner, Hermann, Gudny Eiriksdottir, Timpson, N.J., Schmidt, MK, Paternoster, L, Michailidou, K. (Kyriaki), Ken K. Ong, Lisette Stolk, Storniolo, AM, Ridker, Paul M., Sandra Lai, Koller, D.L. (Daniel), Hottenga, J-J, Winqvist, R. (Robert), Melissa E. Garcia, Couch, Fergus J, Sorensen, Thorkild I. A., Rivadeneira Ramirez, F. (Fernando), Andrulis, Irene L, Harris, Tamara B, Elks, CE, D'adamo, Adamo Pio, Montgomery, G.W. (Grant), Amin, Najaf, Stolk, Lisette, Kutalik, Z, LifeLines Cohort Study, Storniolo, A., Ruth J. F. Loos, Sanna, S, Knight, Julia A, Eiriksdottir, Gudny, Hua Zhao, J., Wolffenbuttel, Bruce H.R., Laura M. Yerges-Armstrong, Dieffenbach, AK, Robin Haring, Crisponi, L, Dunning, A.M., Deborah J. Thompson, Tyrer, Jonathan, Elks, C.E. (Cathy), Hu, F.B., Hottenga, J.-J., Collée, J.M. (Margriet), Jenny Chang-Claude, Tyrer, J, Peter Vollenweider, Postma, Dirkje S., Ben A. Oostra, Pio d'Adamo, A., Giles, Graham G., Georgia Chenevix-Trench, Lindblom, A. (Annika), Wallaschofski, H, Murray, Anna, Zygmunt, M. (Marek), Thorleifsson, G. (Gudmar), Wallaschofski, H., Widen, E., Pylkäs, K., Boerwinkle, Eric, Mcmahon, G. (George), Esko, Toenu, Tikkanen, E., Eiriksdottir, G, Perry, John R. B., Gasparini, P., Pharoah, Paul D.P., Lunetta, Kathryn L., Lai, S, Lawlor, D.A. (Debbie), Boerwinkle, E, Uitterlinden, AG, Haring, R., Bonanni, B, Bandinelli, S., Sovio, U, Masson, G. (Gisli), Gieger, C, Tikkanen, E. (Emmi), Flyger, Henrik, Wagner, E.K., Wagner, Erin K., He, C.Y., Tamara B. Harris, Bolla, MK, Murray, A. (Anna), Unnur Thorsteinsdottir, Schlessinger, D., Qin Wang, Pennell, C.E., van Duijn, CM, Palotie, A, García-Closas, M. (Montserrat), Paul M. Ridker, Heath, Andrew C, Michailidou, Kyriaki, Ferrucci, L. (Luigi), Chasman, Daniel I, Buring, Julie, Maegi, Reedik, Martin, NG, Nolte, IM (Ilja), Bolla, M.K., Foroud, T, Oldehinkel, A.J. (Albertine), Southey, Mellissa C, ?, ?, Salomaa, V, Beckmann, M.W. (Matthias), Garcia, M. (Melissa), Zhao, Jing Hua, Melbye, M. (Mads), Pascal Guénel, Thompson, Deborah J., Guenel, P., Zwart, J-A. (John-Anker), Duijn, Cornelia, Visser, Jenny A., Ridker, Paul, Patrick F. McArdle, Kiel, Douglas P., Stöckl, D. (Doris), Dennis, J, Palotie, A., Demerath, Ellen W, Rice, J.P., Sørensen, Thorkild I. A., Lili Milani, Flesch-Janys, Dieter, Buring, J.E. (Julie), Magnusson, PK, Stöckl, D, Hooning, Maartje J., Guénel, P. (Pascal), Maartje J. Hooning, Bandinelli, Stefania, Tšernikova, N, Pennell, C.E. (Craig), Snieder, H, Chang-Claude, J. (Jenny), Bergmann, Sven, Anton-Culver, H, Kjellqvist, S. (Sanela), McArdle, P.F. (Patrick), Bergmann, S.M. (Sven), Daniel I. Chasman, Loos, R.J.F. (Ruth), Wareham, N.J. (Nick), Sørensen, Thorkild I.A., Loos, Ruth J.F., Collee, J. Margriet, Milani, L, Guo, S.Q., Gudnason, V. (Vilmundur), Hunter, David J, Tsernikova, N., De Vivo, I., Mihailov, E. (Evelin), Crisponi, Laura, Susan Ring, Yerges-Armstrong, L.M., Esko, T, Buring, JE, Peto, Julian, Rice, JP, Chasman, Daniel, Franceschini, Nora, Cousminer, D.L., Nolte, Ilja M., Easton, Douglas F, Rice, John P, Alison M. Dunning, Feenstra, B, Chenevix-Trench, G, Wang, Q., Byrne, E.M., Waldenberger, Melanie, GENICA Network, Diether Lambrechts, Alizadeh, Behrooz Z, Ferrucci, L, Oldehinkel, Albertine J., Knight, J.A., Meir J. Stampfer, van Duijn, C.M., Tikkanen, Emmi, Brenner, H., Elizabeth A. Streeten, Southey, M.C. (Mellissa C.), Peter Devilee, Uitterlinden, A.G. (André), Stampfer, Meir J, McArdle, Wendy L., Vivo, I. (Immaculata) de, Sorensen, Thorkild IA, Giles, G.G. (Graham), Ridker, PM, Couch, FJ, Luigi Ferrucci, Coviello, AD, Fasching, PA, Mägi, R, Lai, S. (Sandra), Waldenberger, M. (Melanie), Ganna, A. (Andrea), Diana L. Cousminer, Chen, JH, Nevanlinna, Heli, De Vivo, I, Ferreira, Teresa, kConFabt LifeLines Cohort Study, Gudnason, V, John L. Hopper, Consortium, I, Neven, P. (Patrick), Eva Albrecht, Devilee, Peter, Elks, Cathy E., Flesch-Janys, D., Mihailov, E, Hoda Anton-Culver, Teumer, A., Anja Rudolph, Tyrer, J., Atsma, F., Chen, J., Demerath, E.W., Wei Q. Ang, Flesch-Janys, D, Schmidt, Marjanka K, Wareham, NJ, Rose, Lynda M., Smith, Albert V., Teumer, A, Alizadeh, B.Z. (Behrooz), Streeten, E.A., McCarthy, M.I., Waeber, Gerard, Ong, Ken K., Daniel L. Koller, Corre, Tanguy, Chanock, S., Demerath, E.W. (Ellen), Lai, S., Byrne, Enda M., Couper, David, Harris, TB, Zygmunt, M., Cousminer, D.L. (Diana), Lunetta, K.L. (Kathryn), Franke, L. (Lude), Garcia, M.E., Wareham, Nicholas J., Dieter Flesch-Janys, Couch, Fergus J., Nohr, Ellen A., Schmidt, M.K., Dirkje S. Postma, Montserrat García-Closas, Fasching, Peter A., Benitez, J, Oostra, B.A. (Ben), Perry, J.R.B., Oostra, BA, Couch, F.J., Angela Cox, Dunning, Alison M., Timpson, Nicholas J., Smith, A.V. (Davey), Jonathan Tyrer, Foroud, T. (Tatiana), Hofman, Albert, Zhao, J.H., Kamila Czene, Mannermaa, A., Eric Boerwinkle, Pylkäs, K, Rudolph, A., Hiltrud Brauch, André G. Uitterlinden, Day, F, Winqvist, R, Patrick Sulem, Peto, J. (Julian), Chang-Claude, J., Hamann, U., Chen, J, Koller, Daniel L., Voelzke, Henry, Stoeckl, Doris, Crisponi, L. (Laura), Lambrechts, D. (Diether), Sørensen, Thorkild I A, Dieffenbach, A.K., Strachan, DP, Hartman, CA, de Geus, Eco Ej, Tanguy Corre, Adamo Pio D’adamo, Karasik, D, Debbie Lawlor, Boyd, H.A., Grant W. Montgomery, Neven, P., Stefania Bandinelli, Spector, TD, Devilee, P. (Peter), Johnson, Andrew D, Brauch, H. (Hiltrud), Collée, J Margriet, Kiel, D.P. (Douglas P.), Hall, P, Benitez, J., Peacock, M. (Munro), Waldenberger, M, Sulem, P., Hu, F.B. (Frank), Rice, J.P. (John), Ferrucci, L., Anton-Culver, Hoda, Järvelin, M-R, Jouke-Jan Hottenga, Peter Kraft, Gudnason, V., Oldehinkel, AJ, Henry Völzke, Antonietta Robino, Econs, Michael J, Henrik Flyger, Martin, N.G., Guénel, Pascal, Kraft, Phillip, Rudolph, A, Magnusson, P.K., Sorensen, T.I.A., Robino, Antonietta, Teresa Ferreira, Strachan, David P, Tikkanen, E, Andrea Ganna, Thorkild I. A. Sørensen, Hunter, David, Ilja M. Nolte, Martin, Nicholas G., Wang, Qin, Albertine J. Oldehinkel, Hu, Frank B, Hofman, Bert, Andrulis, Irene L., Bonnani, B. (Bernardo), Consorti, EGGEGG, Kraft, P., Andrea D. Coviello, Boyd, HA, Patrik K. Magnusson, Heath, A.C. (Andrew), Ong, K.K. (Ken K.), Eriksson, Johan G., Stampfer, M.J., Eco E. J. de Geus, Erik Ingelsson, Ferrucci, Luigi, Buring, Julie E., Masson, G, Bernardo Bonanni, Julia A. Knight, Boomsma, D.I. (Dorret), Spector, Tim D., Coviello, Andrea D, Dunning, AM, Pers, T.H., Czene, K, Buring, J.E., Easton, DF, Wright, Margaret J., Snieder, H., Ulivi, Sheila, Haring, R, Tyrer, J.P. (Jonathan), Jenny A. Visser, Kay-Tee Khaw, Uitterlinden, André, Pouta, Anneli, Kraft, P, Bojesen, S.E. (Stig), Khaw, K-T, Immaculata De Vivo, Mägi, R. (Reedik), Maegi, R, Khaw, K.-T., Hopper, J.L. (John)   +999 more
core   +1 more source

Massively parallel reporter assay confirms regulatory potential of hQTLs and reveals important variants in lupus and other autoimmune diseases

HGG Advances
Summary: We designed a massively parallel reporter assay (MPRA) in an Epstein-Barr virus transformed B cell line to directly characterize the potential for histone post-translational modifications, i.e., histone quantitative trait loci (hQTLs ...
Yao Fu, Jennifer A. Kelly, Jaanam Gopalakrishnan, Richard C. Pelikan, Kandice L. Tessneer, Satish Pasula, Kiely Grundahl, David A. Murphy, Patrick M. Gaffney   +8 more
doaj   +1 more source

Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice

Journal of Lipid Research, 2011
To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analysis between inbred mouse strains MRL/MpJ and SM/J, measuring triglyceride levels at 8 weeks of age in F2 mice fed a chow diet.
Magalie S. Leduc, Rachael S. Hageman, Ricardo A. Verdugo, Shirng-Wern Tsaih, Kenneth Walsh, Gary A. Churchill, Beverly Paigen   +6 more
doaj   +1 more source

Mapping epistatic quantitative trait loci

BMC Genetics, 2014
How to map quantitative trait loci (QTL) with epistasis efficiently and reliably has been a persistent problem for QTL mapping analysis. There are a number of difficulties for studying epistatic QTL. Linkage can impose a significant challenge for finding epistatic QTL reliably. If multiple QTL are in linkage and have interactions, searching for QTL can
Laurie, Cecelia, Wang, Shengchu, Carlini-Garcia, Luciana Aparecida, Zeng, Zhao-Bang   +3 more
openaire   +2 more sources

Nonparametric Functional Mapping of Quantitative Trait Loci [PDF]

Biometrics, 2009
SummaryFunctional mapping is a useful tool for mapping quantitative trait loci (QTL) that control dynamic traits. It incorporates mathematical aspects of biological processes into the mixture model‐based likelihood setting for QTL mapping, thus increasing the power of QTL detection and the precision of parameter estimation.
Yang, Jie, Wu, Rongling, Casella, George
openaire   +3 more sources

Genetic variation and quantitative trait loci associated with developmental stability and the environmental correlation between traits in maize

, 2008
There is limited experimental information about the genetic basis of micro-environmental variance (V-E) (developmental stability) and environmental correlations.
Hill, William G., Malvar Pintos, Rosa Ana, Ordas, Bernardo, Ordás López, Bernardo, Malvar, Rosa A.   +4 more
core   +1 more source

Linkage disequilibrium interval mapping of quantitative trait loci

BMC Genomics, 2006
Background For many years gene mapping studies have been performed through linkage analyses based on pedigree data. Recently, linkage disequilibrium methods based on unrelated individuals have been advocated as powerful tools to refine estimates of gene ...
de Rochambeau Hubert, Abdallah Jihad, Boitard Simon, Cierco-Ayrolles Christine, Mangin Brigitte   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source