Results 171 to 180 of about 2,979,229 (315)
Multifaceted Interventions Based on Education and Recognition to Enhance Nurses' Compliance With Standard Precautions: A Quasi-Experimental Design. [PDF]
Nurs Health SciYildirim M, Seren Intepeler S, Lam SC.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Using Laboratory Experiments to Design Efficient Market Institutions: The case of wholesale electricity markets [PDF]
This paper assesses the contribution of laboratory experiments to the economics of design applied to the electricity industry. The analysis is dedicated to wholesale markets, and reviews the results accumulated to date concerning both the general ...
Celine Jullien, Carine Staropoli
core
Adaptive, Bayesian Experimental Design to Efficiently Determine the Critical Micelle Concentration of a Surfactant. [PDF]
LangmuirHammond M +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Design and Analysis of Composite Panels
, 2006 European aircraft industry demands for reduced development and operating costs, by 20% and 50% in the short and long term, respectively. Contributions to this aim are provided by the completed project POSICOSS (5thFP) and the running follow-up project ...
Rohwer, Klaus +2 more
core
Hybrid modeling for industrial fermentation processes with an "Intra-Batch Experimental Design". [PDF]
J Ind Microbiol BiotechnolLemperle M +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Reduce or not reduce: a practical guide to calculate sample size for various experimental design in studies involving animals. [PDF]
Front PharmacolMazoit JX, Gonin P.
europepmc +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source