Results 271 to 280 of about 823,915 (314)
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Methodological standards in single-case experimental design: Raising the bar
Research in Developmental Disabilities, 2018Single-case experimental designs (SCEDs), or small-n experimental research, are frequently implemented to assess approaches to improving outcomes for people with disabilities, particularly those with low-incidence disabilities, such as some developmental disabilities. SCED has become increasingly accepted as a research design.
Jennifer B. Ganz, Kevin M. Ayres
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Research methodology and experimental design
2017Before moving to the experimental studies in chapter 4 and chapter 0 , this chapter will describe the applied research methodology to empirically test the theoretical models. Specifically, this chapter will provide a detailed overview of the research methodology in terms of experimental setting, the experimental design, as well as the experiment’s ...
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Characterization and optimization of acoustic filter performance by experimental design methodology
Biotechnology and Bioengineering, 2005AbstractAcoustic cell filters operate at high separation efficiencies with minimal fouling and have provided a practical alternative for up to 200 L/d perfusion cultures. However, the operation of cell retention systems depends on several settings that should be adjusted depending on the cell concentration and perfusion rate.
Volker M, Gorenflo +5 more
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Experimental design methodology for hardware-in-the-loop missile performance simulations
International Journal of Intelligent Defence Support Systems, 2010Hardware-in-the-loop (HWIL) simulation can be a cost effective and validated way to assess the performance of missiles. Current experimental practise for HWIL simulations favours the use of Monte Carlo methods. There are often a significant number of interrelated factors that may affect the outcome of a missile/target engagement.
Anna E. Wildegger-Gaissmaier +2 more
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Experimental design methodologies to optimize the CE separation of epinephrine enantiomers
Chromatographia, 1998A capillary electrophoretic method using a chiral selector was optimized by experimental design for the enantioresolution of epinephrine enantiomers. Two ?-cyclodextrins derivatives, namely heptakis-2,6-di-O-methyl?- cyclodextrin and carboxy-methyl-?-cyclodextrin, respectively neutral and charged, were used as chiral selectors employing an uncoated ...
FANALI S +3 more
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Methodology and Experimental Design for the Study of Liposome-Dependent Drugs
2005This chapter describes the concept of liposome-dependent drugs and the rationale for using them. Subsequently, procedures for studying and identifying liposome-dependent drugs are given. The first procedure described is a simple endpoint assay, and methods are given for both adherent and nonadherent cells.
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Journal of Applied Polymer Science, 2012
AbstractThis study describes the application of response surface methodology in the optimization of guar gum microspheres for colon‐specific delivery of metronidazole. The effect of varying the relative percent of the four factors used, that is guar gum, glutaraldehyde, swelling time, and stirring speed, has been systematically investigated for ...
Raj Kumar Shukla, Akanksha Tiwari
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AbstractThis study describes the application of response surface methodology in the optimization of guar gum microspheres for colon‐specific delivery of metronidazole. The effect of varying the relative percent of the four factors used, that is guar gum, glutaraldehyde, swelling time, and stirring speed, has been systematically investigated for ...
Raj Kumar Shukla, Akanksha Tiwari
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Application of experimental design methodology to the study of the synthesis of nucleosides
Bulletin des Sociétés Chimiques Belges, 1988AbstractA factorial design has been used to study the effect of three factors on the reaction between 4‐amino‐8H‐pyrazino[2,3‐c]‐1,2,6‐thiadiazine 2,2‐dioxide and 1,2,3,5‐tetra‐O‐acetyl‐β‐D‐ribofuranose. Reaction conditions have been found in which the usually less abundant N‐8 isomer is selectively obtained.
J. Elguero, P. Goya, A. Martinez
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Political Methodology: Research Design and Experimental Methods
1998Abstract Provides a discussion of issues relating to research design and experimental methods in political science. Issues are elaborated relating to control and random case selection, internal and external validity, identification of mediating variables, and replication.
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Experimental Design Methodologies in the Optimization of Chiral CE or CEC Separations: An Overview
2012In this chapter, an overview of experimental designs to develop chiral capillary electrophoresis (CE) and capillary electrochromatographic (CEC) methods is presented. Method development is generally divided into technique selection, method optimization, and method validation. In the method optimization part, often two phases can be distinguished, i.e.,
Dejaegher, Bieke +2 more
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