Results 311 to 320 of about 2,245,571 (350)
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Experimental design methodologies to optimize the CE separation of epinephrine enantiomers
Chromatographia, 1998A capillary electrophoretic method using a chiral selector was optimized by experimental design for the enantioresolution of epinephrine enantiomers. Two ?-cyclodextrins derivatives, namely heptakis-2,6-di-O-methyl?- cyclodextrin and carboxy-methyl-?-cyclodextrin, respectively neutral and charged, were used as chiral selectors employing an uncoated ...
FANALI S +3 more
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Methodology and Experimental Design for the Study of Liposome-Dependent Drugs
2005This chapter describes the concept of liposome-dependent drugs and the rationale for using them. Subsequently, procedures for studying and identifying liposome-dependent drugs are given. The first procedure described is a simple endpoint assay, and methods are given for both adherent and nonadherent cells.
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Journal of Applied Polymer Science, 2012
AbstractThis study describes the application of response surface methodology in the optimization of guar gum microspheres for colon‐specific delivery of metronidazole. The effect of varying the relative percent of the four factors used, that is guar gum, glutaraldehyde, swelling time, and stirring speed, has been systematically investigated for ...
Raj Kumar Shukla, Akanksha Tiwari
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AbstractThis study describes the application of response surface methodology in the optimization of guar gum microspheres for colon‐specific delivery of metronidazole. The effect of varying the relative percent of the four factors used, that is guar gum, glutaraldehyde, swelling time, and stirring speed, has been systematically investigated for ...
Raj Kumar Shukla, Akanksha Tiwari
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Application of experimental design methodology to the study of the synthesis of nucleosides
Bulletin des Sociétés Chimiques Belges, 1988AbstractA factorial design has been used to study the effect of three factors on the reaction between 4‐amino‐8H‐pyrazino[2,3‐c]‐1,2,6‐thiadiazine 2,2‐dioxide and 1,2,3,5‐tetra‐O‐acetyl‐β‐D‐ribofuranose. Reaction conditions have been found in which the usually less abundant N‐8 isomer is selectively obtained.
J. Elguero, P. Goya, A. Martinez
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Political Methodology: Research Design and Experimental Methods
1998Abstract Provides a discussion of issues relating to research design and experimental methods in political science. Issues are elaborated relating to control and random case selection, internal and external validity, identification of mediating variables, and replication.
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Experimental Design Methodologies in the Optimization of Chiral CE or CEC Separations: An Overview
2012In this chapter, an overview of experimental designs to develop chiral capillary electrophoresis (CE) and capillary electrochromatographic (CEC) methods is presented. Method development is generally divided into technique selection, method optimization, and method validation. In the method optimization part, often two phases can be distinguished, i.e.,
Dejaegher, Bieke +2 more
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DIDACTIC METHODOLOGY BASED ON EXPERIMENTAL DESIGN
INTED Proceedings, 2020Eugenio Llorens +2 more
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Experimental validation of the R³I design evaluation methodology
J. of Design Research, 2011How the validity of an emerging design method or methodology, such as relative reliability risk index (R3I), should be tested and demonstrated remains a vital question for the design research community. This paper provides a review of current thinking about the validation process and via a case study seeks to describe how an appropriate controlled ...
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Experimental Characterization of Simulated PIFA Designed by Parametric Design Methodology
2023 IEEE Wireless Antenna and Microwave Symposium (WAMS), 2023Devashree A. Panchal, V.A. Rana
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