Optimization of Curcumin Nanocrystals as Promising Strategy for Nose-to-Brain Delivery Application
Intranasal (IN) drug delivery is recognized to be an innovative strategy to deliver drugs to the Central Nervous System. One of the main limitations of IN dosing is the low volume of drug that can be administered.
Angela Bonaccorso +7 more
doaj +1 more source
The most common forensic entomological application is the estimation of some portion of the time since death, or postmortem interval (PMI). To our knowledge, a PMI estimate is almost never accompanied by an associated probability. Statistical methods are
Jeffrey Wells, Lynn LaMotte
doaj +1 more source
Tensegrity Structure: Experimental Methodology for Wheelchair Design [PDF]
This experimental research is inserted in the universe of people with special needs and intends to develop a new technology to design the structure of wheelchair. This structure consists of a tensegrity module composed of bamboo sticks and tensioned cables and adopts all the anthropometric standards with the observance to the ergonomic studies and ...
Carlos Mauricio da Costa Ramos +2 more
openaire +1 more source
Extraction of Anthocyanins and Total Phenolic Compounds from Açai (Euterpe oleracea Mart.) Using an Experimental Design Methodology. Part 3: Microwave-Assisted Extraction [PDF]
In this work, two methods based on microwave-assisted extraction techniques for the extraction of both anthocyanins and total phenolic compounds from acai have been developed.
Aliaño González, María José +7 more
core +1 more source
Normalized analysis and design of LCC resonant converters [PDF]
—A normalization of the LCC voltage-output resonant converter performance characteristics, in terms of the tank gain at resonance and the parallel-to-series-capacitor ratio, is presented. The resulting description is subsequently used for the derivation
Bingham, Chris +3 more
core +1 more source
Extraction of Anthocyanins and Total Phenolic Compounds from Acai (Euterpe oleracea Mart.) Using an Experimental Design Methodology. Part 2: Ultrasound-Assisted Extraction [PDF]
Two optimized methods for ultrasound-assisted extraction were evaluated for the extraction of two types of acai bioactive compounds: Total anthocyanins (TAs) and total phenolic compounds (TPCs).
Aliaño González, María José +7 more
core +1 more source
Design methodology for smart actuator services for machine tool and machining control and monitoring [PDF]
This paper presents a methodology to design the services of smart actuators for machine tools. The smart actuators aim at replacing the traditional drives (spindles and feed-drives) and enable to add data processing abilities to implement monitoring and ...
Archimède, Bernard +2 more
core +3 more sources
The Best Location for Speed Bump Installation Using Experimental Design Methodology
Speed bumps, as traffic calming devices, have been extensively used to reduce traffic speed on local streets. This study represents a unique application of experimental design methodology where the effects of some controllable factors in determining the ...
Alireza Khademi +4 more
doaj +1 more source
Most mobile-type hip exoskeletons only assist on a sagittal plane with a single actuator per hip joint for compactness, lightweightness, and low cost. Even though a new concept of hip mechanism that allows assistance not only on a sagittal plane but also
Jongjun Lee +5 more
doaj +1 more source
Extraction of anthocyanins and total phenolic compounds from açai (euterpe oleracea mart.) using an experimental design methodology. part 1: Pressurized liquid extraction [PDF]
Currently, açai is one of the most important fruits present in the world. Several studies have demonstrated its high content in phenolic compounds and anthocyanins.
Aliaño González, María José +7 more
core +1 more source

