Application of Design Simulation and Experimental Design Methodologies to the Study of Coronary Stent Designs [PDF]
AbstractDesign Simulation and Experimental Design are widely used techniques in engineering design studies. Design simulation is useful in the virtual testing of new designs without having to spend resources on creating actual prototypes. Experimental Design is useful in analyzing relationships between various parameters of a design and their impact on
Jared May, Nilesh N. Joshi, Rajeev Nair
openaire +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Design Methodology and Experimental Verification of a Novel Orifice Plate Rectifier
Optimizing the rectification and pressure loss controlled by the aperture structure is challenging, with particular attention paid to the problem of precisely modeling the rectification process of multilayer wire mesh in pulse tube cryocoolers. This work
Zhe Li +5 more
doaj +1 more source
HIGH HYDROSTATIC PRESSURE EXTRACTION OF ANTIOXIDANTS FROM MORINDA CITRIFOLIA FRUIT – PROCESS PARAMETERS OPTIMIZATION [PDF]
A modified version of high hydrostatic pressure extraction has been performed for extraction of antioxidants from M. citrifolia fruit at 5, 15, 25 bar and temperature 30° to 70°C for time duration 1, 2, 4 and 6 hours.
PRAVEEN KUMAR +3 more
doaj
Experimental Design and Validation of an Accelerated Random Vibration Fatigue Testing Methodology
Novel accelerated random vibration fatigue test methodology and strategy are proposed, which can generate a design of the experimental test plan significantly reducing the test time and the sample size.
Yu Jiang +3 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
1-Hexene Polymerization Using Ziegler-Natta Catalytic System with Response Surface Methodology [PDF]
The effects of process conditions and their interactions on the catalyst activity in 1-hexene polymerization were studied with design of experiments by response surface methodology (RSM) using a commercial Ziegler-Natta (ZN) catalyst in the form of TiCl4/
Maliheh Mazaheriyan +3 more
doaj +1 more source
Determinant moments for the design management occurrence in fashion industry [PDF]
Design management has occupied a privileged place in debates related to the field of design and innovation in fashion industry. The apparel industry, in particular, presents a dynamic character, requiring constant updates on raw materials, changes in ...
Libânio, Cláudia de Souza +5 more
core +1 more source

