Results 71 to 80 of about 17,090,036 (281)

Statistical Analysis in Clinical and Experimental Medical Research: Simplified Guidance for Authors and Reviewers

Drug Design, Development and Therapy, 2023
Georgios D Panos,1,2 Frank M Boeckler3,4 1Department of Ophthalmology, Queen’s Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK; 2Division of Ophthalmology and Visual Sciences, School of Medicine, Faculty of Medicine and Health ...
Panos GD, Boeckler FM
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Improved thermal design methodology for wind power converters

Journal of Modern Power Systems and Clean Energy, 2013
This paper presents an improved thermal design methodology for wind power converters. It combines analysis and experimental thermal design tools, including heat transfer correlations, flow network modeling (FNM), computational fluid dynamics (CFD), and ...
Fei Yang, Liang Guo
doaj   +1 more source

A deterministic algorithm for experimental design applied to tomographic and microseismic monitoring surveys [PDF]

, 2004
Most general experimental design algorithms are either: (i) stochastic and hence give different designs each time they are run with finite computing power, or (ii) deterministic but converge to results that depend on an initial or reference design ...
Andrew Curtis, Curtis, A., Lomax, A., Anthony Lomax, Curtis, Andrew; id_orcid, Michelini, A., Alberto Michelini, Leslie, D., David Leslie   +8 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Experimental methodology for analysis of influence of dental implant design on load transfer [PDF]

FME Transactions, 2018
Deformations in the vicinity of dental implants are affected by their design and if threshold level of 0.3 % is surpassed, bone resorption could occur. The goal of this study is to present a novel experimental approch for the analysis of effect od dental
Šarac Dušan Č., Mitrović Nenad R., Tanasić Ivan V., Tihaček-Šojić Ljiljana   +3 more
doaj  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Fostering methodological reasoning in pre-service mathematics teachers: A hypothetical learning trajectory for quasi-experimental design

Infinity
Quasi-experimental designs (QEDs) are widely used in educational research, however pre-service mathematics teachers often struggle to justify their methodological choices when ideal experimental conditions cannot be met. This study designed and refined a
Jeinne Mumu, Lisnani Lisnani, Benidiktus Tanujaya   +2 more
doaj   +1 more source

Study of synthesis parameters of MIL-53(Al) using experimental design methodology for CO/CH separation

Adsorption Science & Technology, 2018
In this study hydrothermal method was used to synthesize MIL-53(Al) (MIL stands for Materials Institute of Lavoisier). Plackett–Burman (P–B) as an experimental design method was applied to investigate the effect of synthesis and activation conditions on ...
Armin Taheri, Ensieh Ganji Babakhani, Jafar Towfighi   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source