Results 81 to 90 of about 823,915 (314)
A New Combined Framework for the Cellular Manufacturing Systems Design [PDF]
Cellular Manufacturing (CM) system has been recognized as an efficient and effective way to improve productivity in a factory. In recent years, there have been continuous research efforts to study different facet of CM system.
Faouzi Masmoudi +2 more
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Evolving Drug Design Methodology: from QSAR to AIDD
, 2022 When medicinal chemistry was born a hundred years ago, a drug design methodology was expected to be based on the knowledge of the relations among chemistry, biology and medicine.
Jun, Xu
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Experimental methodology for analysis of influence of dental implant design on load transfer [PDF]
FME Transactions, 2018 Deformations in the vicinity of dental implants are affected by their design and if threshold level of 0.3 % is surpassed, bone resorption could occur. The goal of this study is to present a novel experimental approch for the analysis of effect od dental
Šarac Dušan Č. +3 more
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Design study of a novel regenerative pump using experimental and numerical techniques
, 2010 This paper presents a numerical and experimental analysis of a new regenerative pump design. The complex flow-field within regenerative pumps represents a significant challenge to previous published mathematical models. The new pump design incorporates a
Quail, Francis J. +2 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
An experimental methodology testing for prudence and third-order preferences [PDF]
We propose an experimental method to test individuals for prudence (i.e. downside risk aversion) outside the expected utility framework. Our method relies on a novel representation of compound lotteries which allows for a systematic parameterization that
Sebastian Ebert, Daniel Wiesen
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Adsorption Science & Technology, 2018 In this study hydrothermal method was used to synthesize MIL-53(Al) (MIL stands for Materials Institute of Lavoisier). Plackett–Burman (P–B) as an experimental design method was applied to investigate the effect of synthesis and activation conditions on ...
Armin Taheri +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
My knot : social design project for awareness of mental discomfort
, 2013 My Knot is a social design project, which embrace various subjects like psychology, social design, semiotic language to define an artistic product that include clothing design and textile design, video design and set design. The project, wants to define
Rorato, Erica
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