Results 101 to 110 of about 823,915 (314)

RESPONSE SURFACE METHODOLOGY APPLIED TO LACCASES ACTIVITIES EXHIBITED BY STENOTROPHOMONAS MALTOPHILIA AAP56 IN DIFFERENT GROWTH CONDITIONS

open access: yesBioResources, 2011
Stenotrophomonas maltophilia AAP56, laccase-producing bacteria, growing under different conditions, exhibit laccase activity that is highly affected by some environmental factors.
Said Galai,   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A design-oriented methodology for accurate modeling of on-chip interconnects [PDF]

open access: yes, 2011
An accurate modeling methodology for typical on-chip interconnects used in the design of high frequency digital, analog, and mixed signal systems is presented.
Reydezel Torres Torres   +2 more
core  

Real-time simulation and control systems design by the Response Surface Methodology and designed experiments [PDF]

open access: yes, 2010
This paper examines two cases where the fitting of a model to experimental data makes possible the solution of extremely difficult design and simulation problems. In the first (aerospace) case, designed experiments were conducted on a permanent magnet AC
Stewart, Paul   +2 more
core   +1 more source

Design Methodology for LED Lighting Systems Based on Photo-Electro-Thermal Interrelationships

open access: yesEletrônica de Potência, 2018
This paper presents a design methodology for LED (Light-Emitting Diode) lighting systems based on photo-electro-thermal (PET) interrelationships. The proposed methodology uses only LED datasheet information, which makes experimental tests unnecessary to
Leandro Chies   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Response Surface Methodology in Biodiesel Production and Engine Performance Assessment

open access: yesInternational Journal of Thermofluids
Biodiesel is a sustainable and green fuel with high potential for mitigating the adverse environmental impacts associated with conventional fossil fuels.
Sara Maen Asaad   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Utilizing experimental design and desirability function in optimizing RP-HPLC method for simultaneous determination of some skeletal muscle relaxants and analgesics

open access: yesScientific Reports
An experimental design and response surface methodologies using Plackett–Burman and Box-Behnken designs were applied for selecting and optimizing the most appropriate parameters which significantly affect the separation and quantitative estimation of ...
Ayoub N. Mozayad   +2 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

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