Results 121 to 130 of about 2,245,571 (350)

Son, are you on Facebook? The impact of parental involvement in school interventions about E-safety [PDF]

, 2015
Media literacy interventions in secondary education typically have a limited impact on the participants’ behavior. Therefore, we developed a new e-safety intervention using a design-based research methodology. In the current study, it
Montrieux, Hannelore, Schellens, Tammy, Valcke, Martin, Vanderhoven, Ellen   +3 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

A Rayleigh-Ritz analysis methodology for cutouts in composite structures [PDF]

A new Rayleigh-Ritz stress analysis methodology that was developed for composite panels containing cutouts is described. The procedure, which makes use of a general assumed displacement field, accommodates circular and elliptical cutouts in biaxially ...
Russell, Steven G.
core   +1 more source

The use of damage as a design parameter for postbuckling composite aerospace structures [PDF]

, 2008
Advanced fibre-reinforced polymer composites have seen a rapid increase in use in aircraft structures in recent years due their high specific strength and stiffness, amongst other properties.
Degenhardt, Richard, Orifici, Adrian, Thomson, Rodney   +2 more
core  

Unraveling the temperature dependence of the yield strength in single-crystal tungsten using atomistically-informed crystal plasticity calculations

, 2015
We use a physically-based crystal plasticity model to predict the yield strength of body-centered cubic (bcc) tungsten single crystals subjected to uniaxial loading.
Ackermann, Alankar, Ali, Argon, Arieli, Arsenlis, Barton, Basinski, Bodner, Bowden, Brinckmann, Brunner, Brunner, Brünig, Bulatov, Bulatov, Cai, Caillard, Caillard, Caillard, Cereceda, Cereceda, Chang, Chaussidon, Chen, Christensen, Christian, Dao, David Cereceda, Deo, Dezerald, Dezerald, Dierk Raabe, Dorn, Drucker, Duesbery, Duesbery, Duesbery, Dumoulin, Erieau, Escaig, Escaig, Estrin, Fish, Franciosi, Franciosi, Franciosi, Franz Roters, Gilbert, Gordon, Gröger, Gröger, Gröger, Gröger, Gröger, Gupta, Hamelin, Hedworth, Henkelman, Hull, Hutchinson, Hölscher, Hölscher, Ito, J. Manuel Perlado, Jaime Marian, Kalidindi, Kitayama, Klopp, Knezevic, Kocks, Koester, Komanduri, Kuchnicki, Lee, Lee, Li, Lim, Lim, Lim, Lin, Lubliner, Ma, Madec, Marichal, Marichal, Martin Diehl, McDowell, Mecking, Monnet, Monnet, Naamane, Narayanan, Pariseau, Patra, Peeters, Pichl, Plimpton, Prager, Proville, Qin, Queyreau, Queyreau, Raabe, Raabe, Raabe, Raffo, Raphanel, Reina, Romaner, Roters, Roters, Roters, Samolyuk, Scarle, Schmid, Seeger, Seeger, Serenelli, Sheng, Sherwood, Soare, Stainier, Starovoitov, Stephens, Stukowski, Swinburne, Takeuchi, Tang, Taylor, Taylor, Taylor, Taylor, Ventelon, Ventelon, Vitek, Vitek, Weinberger, Weinberger, Woodward, Wurster, Yalcinkaya, Yang, Zurek, Zwiesele, Šesták   +145 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

An application of the individual channel analysis and design approach to control of a two-input two-output coupled-tanks system [PDF]

, 2012
Frequency-domain methods have provided an established approach to the analysis and design of single-loop feedback control systems in many application areas for many years.
Murray-Smith, D.J.
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source