Results 111 to 120 of about 823,915 (314)

Experimental methodology report

, 2003
In architectural design and the construction industry, there is insufficient evidence about the way designers\ud collaborate in their normal working environments using both traditional and digital media.

core  

Design of a Virtual Articulator for the Simulation and Analysis of Mandibular Movements in Dental CAD/CAM [PDF]

, 2009
Organised by: Cranfield UniversityThis paper presents a research project aiming at designing a Virtual Articulator in order to simulate and analyze mandibular movements of the human jaw.
Muniozguren, J., Solaberrieta, E., Arias, A., Etxaniz, O., Minguez, R.   +4 more
core  

Training for design of experiments using a catapult

, 2002
Design of experiments (DOE) is a powerful approach for discovering a set of process (or design) variables which are most important to the process and then determine at what levels these variables must be kept to optimize the response (or quality ...
Antony, Jiju, Jiju Antony
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Eliciting narratives from different groups of older respondents. Consideration of methodology and experimental design.

Karl, B. K., Rzitki, A. (2024, April 10-12). Eliciting narratives from different groups of older respondents. Consideration of methodology and experimental design [Conference presentation].
Karl, Katrin, Rzitki, Aldona
core  

Experimental economics: science or what?

, 2007
Do we want experimental economics to evolve into a genuine science? This paper uses the literature on inequity aversion as a case study in warning that we are at risk of losing the respect of other scientific disciplines if we continue to accept the ...
Shaked, A., Binmore, K.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

An algorithm for generating response surface split-plot designs

, 2012
M.PhilIn an industrial experiment, the presence of hard-to-change factors may force the experimenter to use a split-plot type experimental structure. The corresponding Response Surface model then is a linear mixed model. Different design methodologies
Khadim, Mudakkar Mnas
core  

The application of experimental design models in order to optimize the synthesis of geopolymers

MATEC Web of Conferences, 2018
The aim of this work is to propose the methodology and the mathematical tools for the design and development of geopolymeric materials from industrial wastes and by-products.
Kioupis Dimitris, Skaropoulou Aggeliki, Tsivilis Sotiris, Kakali Glikeria   +3 more
doaj   +1 more source