Results 51 to 60 of about 6,428,700 (116)

Practical considerations for optimal designs in clinical dose finding studies [PDF]

open access: yes
Determining an adequate dose level for a drug and, more broadly, characterizing its dose response relationship, are key objectives in the clinical development of any medicinal drug. If the dose is set too high, safety and tolerability problems are likely
Dette, Holger   +2 more
core  

Muffinjaw Designs

open access: yes, 2019
Muffinjaw Designs work featured at USA Marx Library from March 2019 to April 2019. Come enjoy this collection of various sculptures ranging from a variety of mediums like glass and ceramics.https://jagworks.southalabama.edu/vid_presentations/1054 ...
Designs, Muffinjaw
core  

Model-robust and model-sensitive designs. [PDF]

open access: yes
: The main drawback of the optimal design approach is that it assumes the statistical model is known. In this paper, a new approach to reduce the dependency on the assumed model is proposed.
Goos, Peter   +3 more
core  

Experimental Designs

open access: yes, 1957
xiv,601 hal,;ill,;21 ...
Cochran,William G, Cox,Gertrude M
core  

Space-Filling Latin Hypercube Designs For Computer Experiments (Revision of CentER DP 2006-18) [PDF]

open access: yes
In the area of computer simulation, Latin hypercube designs play an important role. In this paper the classes of maximin and Audze-Eglais Latin hypercube designs are considered.
Rennen, G.   +3 more
core  

Field-Scale Experimental Designs and Spatial Econometric Methods for Precision Farming: Strip-Trial Designs for Rice Production Decision Making [PDF]

open access: yes
Site-specific data is spatially variable, precluding traditional econometric analysis. Some field-scale experimental designs present logistical, operational and mathematical problems in estimating treatment differences, specifically when adjacent ...
Florax, Raymond J.G.M.   +2 more
core  

On the number of support points of maximin and Bayesian D-optimal designs in nonlinear regression models [PDF]

open access: yes
We consider maximin and Bayesian D-optimal designs for nonlinear regression models. The maximin criterion requires the specification of a region for the nonlinear parameters in the model, while the Bayesian optimality criterion assumes that a prior ...
Dette, Holger, Braess, Dietrich
core  

Robust designs for series estimation [PDF]

open access: yes
We discuss optimal design problems for a popular method of series estimation in regression problems. Commonly used design criteria are based on the generalized variance of the estimates of the coefficients in a truncated series expansion and do not take ...
Dette, Holger, Wiens, Douglas P.
core  

Performance Testing of Experimental Dowel Bar Retrofit Designs Part 2 - Repeatability and Modified Designs

open access: yes, 2003
Effective load transfer across Portland cement concrete pavement joints significantly decreases pavement deterioration. Dowel bars placed transversely across a joint or crack provide a mechanism for effective load transfer to take place.
Schultz, Arturo E.   +2 more
core  

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