Results 81 to 90 of about 1,227,115 (260)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The importance of attribute interactions in conjoint choice design and modeling. [PDF]
Within the context of choice experimental designs, most authors have proposed designs for the multinomial logit model under the assumption that only the main effects matter.
Goos, Peter +2 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Experimental comparison of millimetre wave power monitor designs [PDF]
The ASDEX Upgrade electron cyclotron resonance heating system [1] uses multi-hole waveguide couplers integrated into the matching mirrors ‘M2’ for power monitoring. While the full Gyrotron output power (105 or 140 GHz, typ.
Schubert Martin +3 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
About Some Properties and Constructions of Experimental Designs
In this paper, we consider the problems related to the determining plan of the experiment performed according to the model of the chemical balance weighing design under additional assumption that the experimental errors are equally negatively correlated.
Bronisław Ceranka, Małgorzata Graczyk
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On Tight Euclidean 6-Designs: An Experimental Result
A finite set n X ⊆ â„n with a weight function w: X → â„ > 0 is called Euclidean t-design in â„ > 0 (supported by p concentric spheres) if the following condition holds:           1 i p i i i S x X w X f d w f S ï³ ï€
Djoko Suprianto
doaj +1 more source

