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Impaired Arteriolar Mechanotransduction in Experimental Diabetes Mellitus
Journal of Diabetes and its Complications, 1999Decreased arteriolar distensibility in diabetes may impair signal transduction mechanisms that are required for converting a pressure stimulus into smooth muscle contraction. These studies aimed to determine if pressure-induced increases in arteriolar intracellular Ca(2+) are altered in diabetes and whether diabetes is associated with alterations in ...
G, Yu, H, Zou, R L, Prewitt, M A, Hill
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Experimental diabetes and its relation to diabetes mellitus
The American Journal of Medicine, 1955Summary A few selected possibilities about the nature, causation and measurement of experimental diabetes have been outlined. A modest comprehension of these experimental experiences should be of some help in the management and study of the disease in man.
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Diabetes Mellitus in Man and Experimental Animals
Annals of Internal Medicine, 1967Excerpt In a recent communication, scientists at the Jackson Laboratory in Bar Harbor, Me., reported a mutation (db) in an inbred strain of mice which is inherited as an autosomal-recessive trait a...
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Methods to Induce Experimental Diabetes Mellitus
2015Dysfunction of the visceral tract has been considered for a long time to be the cause of diabetes mellitus. Bomskov in 1910 reported severe diabetic symptoms in dogs after cannulation of the ductus lymphaticus. This observation, however, could not be confirmed in later experiments (Vogel HG (1963), Unpublished data).
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Experimental Atherosclerosis and Diabetes Mellitus
1992Although the production of arterial lesions in animals fed high fat and cholesterol diets had been described at the beginning of the 20th century, and experimental models of diabetes were available at the time Banting and Best isolated insulin in 1920, it was not until the 1940s that attempts were made to study the interaction of diabetes and ...
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DIABETES MELLITUS: FEATURES OF EXPERIMENTAL MODELLING
2019This review examines experimental modelling methods for diabetes mellitus in laboratory animals. There are presented scientific literary data revealing the development of experimental models of diabetes mellitus, as well as disorders developing in this pathophysiological process by various functional systems of the organism.
Samotrueva, Marina A. +1 more
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[Renal prostanoids in experimental diabetes mellitus].
Voprosy meditsinskoi khimii, 1995Participation of renal prostanoids in development of diabetes-induced nephropathy was studied in rats with streptozotocin diabetes. Development of diabetic nephropathy occurred with simultaneous decreases in production of intrarenal natriuretic, depressor prostaglandin and prostacyclin as well as with increases in content of antinatriuretic, pressor ...
A G, Kucherenko +3 more
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[Calcitonin antibodies in experimental diabetes mellitus].
Biulleten' eksperimental'noi biologii i meditsiny, 1985Antibodies to calcitonin appear in blood of rats with experimental alloxan diabetes. This phenomenon is observed only under high blood sugar. At the stage of latent diabetes, i.e. during alloxan administration to the body and low blood sugar no antibodies to calcitonin are detected.
L I, Kulikova +3 more
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Intrarenal fibrinolysis in experimental diabetes mellitus
The Histochemical Journal, 1984U, Fuchs, J, Graff
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