Results 91 to 100 of about 4,610,690 (301)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Computational and experimental investigation of mixing in microchannels [PDF]
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +6 more
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In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Experimental investigation of a SMC high precision control [PDF]
In this paper a discrete-time Sliding-Mode (SM) based controller for high accuracy position control is investigated. The controller is designed for a general SISO system with nonlinearity and external disturbance. It will be shown that application of the
Abidi, Khalid Seyed +2 more
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Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Experimental investigation of piloted flameholders [PDF]
Four configurations of piloted flameholders were tested. The range of flame stabilization, flame propagation, pressure oscillation during ignition, and pressure drop of the configurations were determined.
Guo, C. F., Xie, Q. M., Zhang, Y. H.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The paper reported two-phase flow pressure drop results of R22 during condensation in a horizontal stainless steel rectangular microchannel with the hydraulic diameter of 0.952 mm. Tests were conducted with saturation temperatures of 40-50oC, mass fluxes
Liu Na, Li Junming
doaj
Literature review and experimental investigation of heat pipes [PDF]
Tests on heat pipes determine operational limits, external boundary conditions, noncondensable gas effects, startup behavior, and geometric configurations.
Barsch, W. O. +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

