Results 101 to 110 of about 4,610,690 (301)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Wiadomosci lekarskie (Warsaw, Poland : 1960), 2016 The search for the most perfect way of hollow organ obturation has been done through the history of gastro-intestinal tract surgery. lmi present time sucn aspects of the problem asmorphological changes peculiarities in the process of intestine wound repair in the zone of anastomosis and biological impermeabilty of intestine fistula, possibilities of ...
A I, Protopopova +2 more
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Experimental Determination of Sound Transmission Loss Indices of a Rectangular Plate with Energy-Absorbing Coating [PDF]
Учёные записки Казанского университета: Серия Физико-математические науки, 2015 This paper presents the results of experimental determination of sound transmission loss indices of a rectangular plate with energy-absorbing coating, which were obtained in the reverberation acoustic laboratory and intended to verify the data of ...
V.N. Paimushin +2 more
doaj
Strengthening of Masonry Columns with BFRCM or with Steel Wires: An Experimental Study
Fibers, 2016 Nowadays, innovative materials are more frequently adopted for strengthening historical constructions and masonry structures. The target of these techniques is to improve the structural efficiency with retrofitting methods while having a reduced ...
Marinella Fossetti, Giovanni Minafò
doaj +1 more source
Experimental Investigation on the Behavior of Artificial Magnetic Cilia [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Reputation or Reciprocity? An Experimental Investigation [PDF]
Recent evidence highlights the importance of social norms in many economic relations. However, many of these relationships are long-term and provide repeated game incentives for performance.
Armin Falk, Simon Gaechter
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source