Results 231 to 240 of about 1,685,366 (294)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Prediction of Spectral Parameters in Er³⁺, Dy³⁺ and Nd³⁺ Doped Oxide Glasses via cGAN-Enhanced Hybrid Modeling. [PDF]

Sensors (Basel)
Xie L, Yang H, Wang X.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Expert evaluation of LLM world models: A high-T_<i>c</i> superconductivity case study. [PDF]

Proc Natl Acad Sci U S A
Guo H, Tikhanovskaya M, Raccuglia P, Vlaskin A, Co C, Liebling DJ, Ellsworth S, Abraham M, Dorfman E, Armitage NP, Feng C, Georges A, Gingras O, Kiese D, Kivelson SA, Oganesyan V, Ramshaw BJ, Sachdev S, Senthil T, Tranquada JM, Brenner MP, Venugopalan S, Kim EA.   +22 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Environmental and Prenatal Exposure to Persistent Organic Pollutants and the Risk of Asthma and Respiratory Outcomes Across the Lifespan: A Review of Emerging Epidemiological Evidence and Mechanisms. [PDF]

Cureus
Vittorakis E, Vittorakis E, Kastanakis SG.   +2 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Erratum: Reply to "Comment on 'Evaluation of the Long-Term Administration of Proton Pump Inhibitors (PPIs) in the Mineral Nutrient's Bioavailability'". [PDF]

ACS Omega
de Brito AS, do Nascimento AN, Fonseca FLA, Fioroto AM, Petri G, do Nascimento RGV.   +5 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Effect of Curvature Height on the Low-Velocity Impact Behaviour of Unidirectional T300/5208 CFRP Laminated Shell Panels: A Comparative Numerical Parametric Analysis of Intralaminar + Interlaminar and Intralaminar-Only Models. [PDF]

Polymers (Basel)
Gök O.
europepmc   +1 more source