Results 181 to 190 of about 11,675,419 (289)

Characterization of Comorbid Posttraumatic Stress Disorder and Major Depressive Disorder Using Ketamine as an Experimental Medicine Probe ^†. [PDF]

J Psychiatr Brain Sci, 2021
Albott CS, Lee S, Cullen KR, Thuras P, Lissek S, Wels J, Friedrich KJ, Krueger AM, Lim KO.   +8 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis-2 (AuToDeCRA-2) Study: Protocol for a single-centre, experimental medicine study investigating the route of delivery and potential efficacy of autologous tolerogenic dendritic cell (TolDC) therapy for Rheumatoid Arthritis [PDF]

Trials
Long E, Stanway J, White M, Goudie N, Phillipson J, Morton M, Malek AA, Brown P, Hide G, Jackson R, Nice C, Tuckett J, Diboll J, Anderson A, Pratt A, Hilkens CM, Isaacs J.   +16 more
europepmc   +2 more sources

Building an international platform for the research, development, and dissemination of new knowledge in the field of laboratory animal science, technology, and experimental medicine. [PDF]

Animal Model Exp Med
Choudhary MI.
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Clinical predictors of flare and drug-free remission in rheumatoid arthritis: preliminary results from the prospective BIO-FLARE experimental medicine study. [PDF]

BMJ Open
Rayner F, Hiu S, Melville A, Bigirumurame T, Anderson A, Dyke B, Kerrigan S, McGucken A, Prichard J, Shahrokhabadi MS, Hilkens CMU, Buckley CD, McInnes IB, Ng WF, Goodyear C, Teare D, Filer A, Siebert S, Raza K, Pratt A, Baker KF, Isaacs J.   +21 more
europepmc   +1 more source

The effects of lisdexamfetamine dimesylate on eating behaviour and homeostatic, reward and cognitive processes in women with binge-eating symptoms: an experimental medicine study. [PDF]

Transl Psychiatry, 2022
Schneider E, Martin E, Rotshtein P, Qureshi KL, Chamberlain SR, Spetter MS, Dourish CT, Higgs S.   +7 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

iLABMED: A Translational Medical Journal Embracing a New Era

iLABMED
Tetsuya Asakawa, Yi‐Wei Tang, Hongzhou Lu   +2 more
doaj   +1 more source

Message from animal models and experimental medicine for 2024-Striving for excellence with distinctive features. [PDF]

Animal Model Exp Med
Qin C.
europepmc   +1 more source