Results 131 to 140 of about 325,075 (311)

Experimental plan

This deliverable will describe the experiments to be executed in IMPETUS to test the feasibility of the proposed solution.
openaire   +3 more sources

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

A hierarchical approach to multi-project planning under uncertainty. [PDF]

We survey several viewpoints on the management of the planning complexity of multi-project organisations under uncertainty. A positioning framework is proposed to distinguish between different types of project-driven organisations, which is meant to aid ...
Wullink, G, Hans, EW, Herroelen, Willy, Leus, Roel   +3 more
core  

Tolerability and safety of magrolimab (ONO-7913) in Japanese patients with advanced or metastatic solid tumors: a phase 1, open-label, uncontrolled, dose-escalation study

BMC Research Notes
Objective Magrolimab (ONO-7913) is an anti-cluster of differentiation 47 (CD47) monoclonal antibody. This was a phase 1, open-label, uncontrolled, dose-escalation study that assessed the tolerability and safety of intravenous magrolimab (priming dose: 1 ...
Takafumi Koyama, Toshio Shimizu, Shunsuke Kondo, Yuki Katsuya, Kazuki Sudo, Tatsuya Yoshida, Kan Yonemori, Keiji Matsumoto, Noboru Yamamoto   +8 more
doaj   +1 more source

Experimental Planning for LYNM Source

, 2016
This document describes the mathematical statistical approaches to design, objectives, and other methods of analysis pertaining to the LYNM source.
Brian Williams, Dale Anderson
openaire   +2 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Progress in AI planning research and applications

, 2002
Planning has made significant progress since its inception in the 1970s, in terms both of the efficiency and sophistication of its algorithms and representations and its potential for application to real problems.
Long, D., Fox, M.
core  

Heuristics for planning with sat and expressive action definitions [PDF]

, 2015
We present the first effective SAT heuristics for planning with expressive planning languages such as ADL. Recently, SAT heuristics for STRIPS planning have been introduced.
Jussi Rintanen, Rintanen, Jussi
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

DEM study of fines content effects on shear strength of binary mixtures under low confining pressure

Scientific Reports
The presence of fines in granular materials significantly affects their shear strength, particularly under low confining pressure conditions. In this study, drained triaxial compression tests were simulated using the discrete element method on spherical ...
Hu Tiantian, Gao Zhicheng, Zhang Chaojie, Wang Jing   +3 more
doaj   +1 more source