Results 51 to 60 of about 325,075 (311)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Generalized Linear Integer Numeric Planning

open access: yes, 2022
Classical planning aims to find a sequence of actions that guarantees goal achievement from an initial state. The representative framework of classical planning is based on propositional logic.
Su, K   +11 more
core   +1 more source

The Influence of the Geometry of Grooves on the Operating Parameters of the Impeller in a Centrifugal Pump with Microgrooves

open access: yesEnergies
Centrifugal pumps are one of the most widely used machines in all branches of industry. For this reason, their efficiency has a significant impact on energy consumption in global industry (about 20%).
Marcin Bieganowski   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tamanho de parcelas experimentais para Eucalyptus saligna Smith Experimental plot size for Eucalyptus saligna Smith

open access: yesCiência Rural, 1997
O objetivo deste trabalho foi estimar o tamanho ótimo de parcelas experimentais de Eucalyptus saligna Smith, aos 15 meses de idade e aos 5 anos e meio de idade.
Magda Lea Bolzan Zanon, Lindolfo Storck
doaj   +1 more source

Comprehensive 5P framework for active aging using the ecological approach: an iterative systematic review

open access: yesBMC Public Health, 2020
Background “Active aging” is an inclusive term and has been defined from a variety of aspects in different domains throughout the literature. The aim of this review was to identify those aspects that play significant roles in building this concept using ...
Azadeh Lak   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Tamanho de amostra para estimação do coeficiente de correlação de Pearson entre caracteres de Crambe abyssinica Sample size to estimate the Pearson correlation coefficient among characters of Crambe abyssinica

open access: yesRevista Ciência Agronômica, 2011
É importante dimensionar adequadamente o tamanho de amostra, para estimação, com confiabilidade aceitável, do coeficiente de correlação linear de Pearson entre pares de caracteres.
Alberto Cargnelutti Filho   +4 more
doaj   +1 more source

Correction to: Comprehensive 5P framework for active aging using the ecological approach: an iterative systematic review

open access: yesBMC Public Health, 2020
It was highlighted that the original article [1] contained a spelling mistake in the name of Hamid R. Baradaran. This was incorrectly captured as Bradaran. The original article has been updated.
Azadeh Lak   +3 more
doaj   +1 more source

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