Results 121 to 130 of about 11,455,032 (320)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Experimental planning for the evaluation of phenotipic descriptors in banana

Revista Brasileira de Fruticultura, 2018
This work aimed to subsidize experimental planning for the evaluation of phenotypic characters in banana. The experiment consisted of a uniformity trial with Tropical cultivar spaced of 3 m x 2 m, in a useful area with nine rows of 40 plants.
Sérgio Luiz Rodrigues Donato, João Abel da Silva, Bruno Vinícius Castro Guimarães, Sebastião de Oliveira e Silva   +3 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Índice de heterogeneidade, coeficiente de variação e tamanho ótimo de parcela em batata Heterogeneity index, variation coefficient and optimal potato plot size

Ciência Rural, 2006
O objetivo deste trabalho foi avaliar a relação entre o coeficiente de variação das parcelas de uma cova e o índice de heterogeneidade com o tamanho ótimo de parcela para experimentos com batata.
Sérgio José Ribeiro de Oliveira, Lindolfo Storck, Alessandro Dal'Col Lúcio, Sidinei José Lopes, Luiz Fernando Dias Martini   +4 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Tamanho de amostra para experimentos com feijão-de-vagem em diferentes ambientes Sample size for experiments with bean pods in different environments

Ciência Rural, 2011
Com o objetivo de estimar o tamanho de amostra para a fitomassa fresca de vagens de feijão-de-vagem, foram realizados cinco experimentos em branco com a cultivar 'Macarrão' no outono/inverno de 2009 e na primavera/verão de 2010, em estufa, túnel e a ...
Fernando Machado Haesbaert, Daniel Santos, Alessandro Dal’Col Lúcio, Vilson Benz, Bruno Ioppi Antonello   +4 more
doaj   +1 more source

A precision sprayer capable of whole-of-block precision experimentation in viticulture

The French Wine and Vine Institute and INRAE have developed innovative methods to study the factors of plant protection product efficacy under real vineyard conditions, employing whole-of-block precision experimentation principles. From 2021 to 2023, a partnership with OPTIMA Concept ® and Berthoud ® allowed to develop a high-precision sprayer tailored
Codis, Sébastien, Delpuech, Xavier, Lewis, Maude, Bellone, Davide, Ribeyrolles, Xavier, Vergès, Adrien, Naud, Olivier   +6 more
openaire   +2 more sources

Balancing Precision and Retention in Experimental Design

Political Analysis
Abstract In experimental social science, precise treatment effect estimation is of utmost importance, and researchers can make design choices to increase precision. Specifically, block-randomized and pre-post designs are promoted as effective means to increase precision.
Gustavo Diaz, Erin Rossiter
openaire   +1 more source

The modern description of semileptonic meson form factors [PDF]

, 2006
I describe recent advances in our understanding of the hadronic form factors governing semileptonic meson transitions. The resulting framework provides a systematic approach to the experimental data, as a means of extracting precision observables ...
Hill, Richard J.
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source