Results 121 to 130 of about 10,600,838 (308)
Site-specific treatment responses in on-farm precision experimentation
, 2019 There is a large body of research on determining the impact of field variability of soil on crop yields. In contrast, site-specific information about crop responses to agronomic treatments is less frequent. On-Farm Precision Experimentation (OFPE) brings important information to understand the spatial variation of crop response to agronomic practices ...
Rodrigo Gonçalves Trevisan +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Precise distance measurement with stereo camera: experimental results
PeerJ Computer ScienceToday, image processing is used in many areas, especially artificial intelligence. This is because images are thought to contain a lot of information. In addition, many distance measurement studies have used image processing techniques. However, no studies have reached these high sensitivity and accuracy rates that can be used in engineering.
Haydar Yanik, Bülent Turan
openaire +4 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Stem Cell Research & TherapyBackground Mesenchymal stem cells (MSCs)-derived exosomes present great potential as nanocarriers for targeted drug delivery. Moreover, the therapeutic efficacy of exosomes can be substantially enhanced through functional modifications and the ...
Xiao-huan Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Optimal plot size for the evaluation of phenotypic traits in soybean seedlings
Crop Breeding and Applied BiotechnologyPhenotypic traits with discriminatory capacity have been studied in recent years. However, scientific studies often employ experimental plots of varying sizes.
Tiago de Avila Silva +5 more
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Border effect on the agronomic evaluation of wheat cultivars
Crop Breeding and Applied BiotechnologyThe aim of this study was to assess the border effect in wheat agronomic trials in Minas Gerais, Brazil. Experiments were conducted in three environments using 16 cultivars in plots of five rows (two outer rows as the border area).
Alan Diego do Rosário Chaves +13 more
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