Results 111 to 120 of about 10,498,087 (284)
Multidisciplinary research in the space sciences. Scope B: Experimental X-ray astronomy [PDF]
A research program to design and develop instruments suitable for rocket-borne X-ray astronomy experiments is discussed. Successful designs that were implemented are summarized.
Novick, R.
core +1 more source
To P or not to P: on the evidential nature of P-values and their place in scientific inference [PDF]
, 2013 The customary use of P-values in scientific research has been attacked as being ill-conceived, and the utility of P-values has been derided. This paper reviews common misconceptions about P-values and their alleged deficits as indices of experimental ...
Lew, Michael J.
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A Conceptual Framework for Religiousity Survey in Iran [PDF]
Islām va ̒ulūm-i ijtimā̒īIn analyzing the complex issue of religion, social science researchers require an operational definition aside from the logical and conceptual definitions of religion and religiousity.
Mohammad Reza Taleban
doaj
Experimental research of a new generation of support systems for the transport of mineral raw materials [PDF]
, 2017 Within the transportation of materials in mining using the belt conveyor systems, a conveyor belt is particularly the component with the highest wear rate.
Ambriško, Ľubomir +3 more
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
“EFEKTIFITAS METODE KONVENSIONAL DAN FLASHCARD UNTUK MENINGKATKAN KEMAMPUAN KOSAKATA BAHASA INGGRIS ANAK SEKOLAH DASAR” [PDF]
In learning English, problems often arise, especially for the students themselves, this can be seen from the EPI (English Proficiency Index) This research uses an experimental method by taking samples from 20 experimental classes and 18 control classes ...
Herwandi, Luthfi Alifa
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source