Results 141 to 150 of about 58,403,547 (305)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The methodology of multi objective design of active-passive shielding system for overhead power lines magnetic field in residential buildings space based on metaheuristic optimization method

Electrical engineering & Electromechanics
Problem. Most studies of power frequency magnetic field reduced to safe level in in residential buildings located near overhead power lines carried out based on passive or active electromagnetic shielding, but there is no methodology for designing active-
B. I. Kuznetsov, A. S. Kutsenko, T. B. Nikitina, I. V. Bovdui, K. V. Chunikhin, V. V. Kolomiets   +5 more
doaj   +1 more source

The Experimental Animal in Research [PDF]

Nature, 1964
openaire   +2 more sources

Películas españolas [PDF]

, 1945
Cine experimental (1945). Películas españolas. Cine experimental. (4):252-254.
Cine experimental
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Health Research Board: Health Research in Action [PDF]

This year’s Health Research in Action highlights some of the many notable impacts and outcomes of our work. It includes a snapshot in numbers of recent work completed, followed by 19 success stories about wide-ranging health and social care research ...
Health Research Board
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Simulation and Experimental Research of Air Conditioning and Ventilating System for Intercity Train

机车电传动, 2020
In intercity vehicle, the air conditioning and ventilation system has an important impact on breeze speed, temperature and humidity of which directly affects the thermal comfort of passengers.
Shujuan SUN, Xin LIN
doaj  

Para estrenar [PDF]

, 1946
Cine experimental (1946). Para estrenar. Cine experimental. (9):137-138.
Cine experimental
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source