Results 81 to 90 of about 10,497,983 (264)
Experimental Research on 4-Duct Tandem VTOL Aircraft Configurations [PDF]
This paper presents a brief summary of several wind-tunnel investigations conducted at the Langley Research Center of the NASA to study the aerodynamic and stability and control characteristics of several VTOL aircraft configurations powered by four ...
Mc Kinney, M. O., Newsom, W. A.
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Otto Stern (1888-1969): The founding father of experimental atomic physics
, 2011 We review the work and life of Otto Stern who developed the molecular beam technique and with its aid laid the foundations of experimental atomic physics.
Friedrich, Bretislav +3 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Experimental design for research on shock-turbulence interaction [PDF]
, 1969 Report investigates the production of acoustic waves in the interaction of a supersonic shock and a turbulence environment. The five stages of the investigation are apparatus design, development of instrumentation, preliminary experiment, turbulence ...
Radcliffe, S. W.
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Experimental study of the pharmacokinetics of monoclonal antibodies to α4β1-integrin in guinea pigs
Биопрепараты: Профилактика, диагностика, лечение, 2018 This article presents the data on pharmacodynamics evaluation of monoclonal antibodies to α4β1-integrin in guinea pigs. The effect on total content of peripheral blood leukocytes after a single intraperitoneal injection of three doses of the drug has ...
B. N. Krapivin +2 more
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Elm Farm Research Centre: Sheepdrove Organic Farm (experimental farm) [PDF]
Sheepdrove Organic Farm – 800 ha downland organic farm in southern England. Mixed farm of arable, forage, beef, pigs and silvo-poultry. Office and meeting facilities.
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Estimation of Uniaxial Compressive Strength and Tensile Strength of Sandstone Based on Point Load
Renmin ZhujiangIn rock mechanics and engineering practice, accurate and rapid evaluation of uniaxial compressive strength and tensile strength of rock is important for engineering design and construction safety. Traditional test methods are time-consuming and laborious,
LIU Yongzhi +5 more
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source