Results 41 to 50 of about 5,472,250 (305)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Experiences and results with a cementless femoral stem design: SL-PLUS MIA
Aim: To evaluate the outcomes of the SL-PLUS® MIA cementless femoral stem (Smith & Nephew Orthopedics AG, Switzerland) application using the modified lateral approach. Method: Demographic and clinical data, in addition to the operational outcomes of 42
Köken, Murat +6 more
core +2 more sources
. The paper presents an analysis of an isotropic circular axisymmetric perforated plate loaded with concentrated force Pi applied in the geometric center of the plate using finite element software ANSYS.
Mateusz Konieczny +2 more
doaj +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Karst geology creates a complex environment with diverse landforms, blurred boundaries, and multi-factor interactions. This paper presents a new drilling pile installation method: drill to a set depth, clean the hole, insert prefabricated piles, and ...
Yi Wang +5 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Periarticular injury usually causes the defects of superficial cartilage and the underlying subchondral bone. Although some efficacious outcomes have been achieved by the existing therapeutic methods both in clinics and research, like symptomatic ...
Bingchuan Liu +17 more
doaj +1 more source
Experimental researches in electricity [PDF]
Abstract This paper is divided into four parts: the first being on the Induction of Electric Currents; the second, on the Evolution of Electricity from Magnetism; the third, on a new Electrical Condition of Matter; and the fourth, on Arago’s Magnetic Phænomena.
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

