Results 101 to 110 of about 8,711,360 (296)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Augmented Reality for Mathematics Learning: A Study for Enhancing Mathematical Comprehension in High School Students

JTAM (Jurnal Teori dan Aplikasi Matematika)
Numerous initiatives have sought to incorporate novel learning environments or technology, including Augmented Reality, into delivering more comprehensive education.
Wanda Nugroho Yanuarto, Elfis Suanto, Mohamad Galang Isnawan   +2 more
doaj   +1 more source

Alpha-cluster Condensations in Nuclei and Experimental Approaches for their Studies

, 2010
The formation of alpha-clusters in nuclei close to the decay thresholds is discussed. These states can be considered to be boson-condensates, which are formed in a second order phase transition in a mixture of nucleons and alpha-particles. The de Broglie
A. Tohsaki, A.N. Danilov, Audi G., D.T. Khoa, F. Hoyle, F.S. Stephens, H. Feldmeier, H. Horiuchi, H. Horiuchi, H. Horiuchi, J. Pochodzalla, M. Chernych, M. Freer, P. Schuck, P. Schuck, P. Schuck, R. Broglia, S. Thummerer, S. Thummerer, S. Torilov, T. Glasmacher, T. Kokalova, T. Kokalova, T. Neff, T. Wakasa, T. Yamada, U.A. Wiedemann, V. Bradnova, V. V. Zherebchevsky, V.I. Isakov, W. Oertzen von, W. Oertzen von, W. Oertzen von, W. Oertzen von, W. Oertzen von, W. Oertzen von, Y. Funaki, Y. Funaki, Y. Kanada-En’yo   +38 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Review on Bioactive Compounds and Pharmacological Activities of Citrus unshiu

Applied Sciences
Citrus constitutes a group of fruit crops that include lemons, limes, mandarins, oranges, and grapefruits. These citrus have a variety of essential nutrients and bioactive compounds that exert several pharmacological properties, including antioxidant ...
Naser A. Alsharairi
doaj   +1 more source

Experimental electron shielding studies Technical summary report [PDF]

Electron shielding - comparison of thick target energy straggling and angular distributions with Monte Carlo ...
Jupiter, C. P., Merkel, G.
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Automated detection of sleep spindles in the scalp EEG and estimation of their intracranial current sources: Comments on techniques and on related experimental and clinical studies

Frontiers in Human Neuroscience, 2014
Periklis Y. Ktonas, Errikos-Chaim eVentouras   +1 more
doaj   +1 more source

A systematic review on experimental studies about patient adherence to treatment

Pharmacology Research & Perspectives
A better understanding of patients' adherence to treatment is a prerequisite to maximize the benefit of healthcare provision for patients, reduce treatment costs, and is a key factor in a variety of subsequent health outcomes.
Frans Folkvord, Ana Roca‐Umbert Würth, Karlijn vanHouten, Aad R. Liefveld, Jim Ingebretsen Carlson, Nadine Bol, Emiel Krahmer, Gwenn Beets, Rachel Drbohlav Ollerton, Eva Turk, Harald Hrubos‐Strøm, Hamza Nahoui, Gunnar Einvik, Henrik Schirmer, Anne Moen, Jaime Barrio‐Cortes, Beatriz Merino‐Barbancho, Peña Arroyo, Giuseppe Fico, Luís Midão, Rute Sampaio, João A. Fonseca, Katja Geipel, Kathrin Scheckenbach, Laura E. deRuiter, Francisco Lupiáñez‐Villanueva   +25 more
doaj   +1 more source

Experimental studies on the “Phantom Yaw Effect” at maneuvering slender bodies [PDF]

, 2011
Asymmetric vortices can occur unexpectedly on slender bodies at high angles of attack. These vortices separating from the nose or/and shoulder region induce a side force and also a corresponding yawing moment often referred to as "phantom yaw".
Schülein, Erich, Wysocki, Oliver
core