Results 231 to 240 of about 11,529,415 (339)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

An Experimental Study on the Impact of Survey Stakes on Response Inconsistency in Mixed-Worded Scales. [PDF]

Educ Psychol Meas
Michaelides MP, Konstantinidou E.
europepmc   +1 more source

Experimental investigation of solar photovoltaic panel convective cooling: Turbulence-reduced wind tunnel study

Ivan Čorić, Sandro Nižetić, Mišo Jurčević, Ivo Marinić-Kragić, Duje Čoko   +4 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Helicosphaera carteri (Prymnesiophyceae) under high carbon dioxide: An experimental study. [PDF]

J Phycol
Bianco S, Bordiga M, Langer G, Ziveri P, Cerino F, Relitti F, Laudicella VA, Di Giulio A, Lupi C.   +8 more
europepmc   +1 more source

Table 1_Pediatric healthcare service utilization after the end of COVID-19 state of emergency in Northern Italy: a 6-year quasi-experimental study using interrupted time-series analysis.docx

Matteo Puntoni (4901191), Caterina Caminiti (3412628), Giuseppe Maglietta (12992976), Marcello Lanari (3533234), Giacomo Biasucci (5412437), Agnese Suppiej (11782133), Federico Marchetti (167802), Alessandro De Fanti (16361411), Fabio Caramelli (8117402), Lorenzo Iughetti (830764), Chiara Ghizzi (15228626), Enrico Valletta (65730), Gianluca Vergine (18403392), Marcello Stella (8482674), Beatrice Campana (22099826), Valentina Fainardi (12222593), Michela Deolmi (21027068), Susanna Esposito (397772), Emilia-Romagna Paediatric COVID-19 Network (22099829)   +18 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

An experimental study of the effect of electric field enhancement on the adsorption characteristics of coalbed methane. [PDF]

Sci Rep
Chen Z, Liu H, Han W, Li H.
europepmc   +1 more source

Data from "Experimental study of the unsteady vibration signature for a Sirocco fan unit"

Argüelles Díaz, Katia María, Fernandez Oro, Jesus Manuel, Pérez González, José   +2 more
openalex   +1 more source