Results 81 to 90 of about 251,407 (198)
Tikrit Journal of Engineering Sciences, 2016 This paper has presented an experimental study of quasi-static compressive and tensile loading of cutout hole on multi-layer of Kevlar-29/epoxy-Al2O3laminated composite.
Ayad A. Ramadhan
doaj
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Efficiency Improvement of Switched Reluctance Generator Using Optimization Techniques
Transactions on Environment and Electrical Engineering, 2017 This article introduces the switched reluctance machine operating as a generator. This kind of electrical machine delivers CC power at the output and the energy generated can be controlled through several variables.
Márcio Rodrigues da Cunha Reis +2 more
doaj +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Histo-morphological study of functional overload (Clinical experimental study)
Romanian Journal of Oral Rehabilitation, 2018 Traumatic occlusion function is a continuous overload of dental system in chewing function which causes various damage in periodontal. This overload is visible not only in the full dental system, but also in the lack of teeth. Histo-morphological changes
Alketa QAFMOLLA +2 more
doaj
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
MicroorganismsProkaryotes play a key role in particulate organic matter’s decomposition and remineralization processes in the vertical scale of seawater, and prokaryotes contribute to more than 70% of the estimated remineralization.
Hao Liu, Hongmei Jing
doaj +1 more source
STUDIES ON EXPERIMENTAL PORPHYRIA
Nihon Naika Gakkai Zasshi, 1964 Porphyriaの病態は来だ解明されたとは言い難く,動物実験の成績も充分とは云い難い.著者はhexachlorobenzeneを家兎に経口投与することにより,ヒトの急性間欠性porphyriaに類似した臨床症状および尿所見を起こし得た,この実験家兎において尿中porphyrin体,プリン体,クレアチンおよび既成クレアチニンの変動,血清transaminase, cholinesterase活性,肝および赤血球のcatalase活性の変化を経過に従い測定した.又経過中に観察された筋萎縮および全身痙攣の本態を解明するため,筋電図検索を行ない, myogenicおよびneurogenic atrophyを示唆する所見を得た.筋生検の結果,電顕的にも光顕的に屯筋萎縮を示す所見を得た ...
openaire +4 more sources