Results 171 to 180 of about 1,169,893 (336)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Cannabis expectancies mediate the association between social media use and cannabis experimentation in early adolescents: A prospective cohort study. [PDF]

Drug Alcohol Depend
Nagata JM, Caffrey A, Nguyen ND, Nayak S, Frimpong I, Helmer CK, Ricklefs C, Al-Shoaibi AA, Testa A, Brindis CD, Santos GM, Baker FC.   +11 more
europepmc   +1 more source

A calibrated UV LED light source for photocatalytic experimentation [PDF]

, 2016
Aleksandrs Sergejevs, Christopher Clarke, D.W.E. Allsopp, Javier Marugán, Chris Bowen   +4 more
openalex  

Supplementary Table 1 from Cigarette Experimentation in Mexican Origin Youth: Psychosocial and Genetic Determinants

, 2023
Anna V. Wilkinson, Melissa L. Bondy, Xifeng Wu, Jian Wang, Qiong Dong, Anthony M. D’Amelio, Alexander V. Prokhorov, Xia Pu, Robert K. Yu, Carol J. Etzel, Sanjay Shete, Margaret R. Spitz   +11 more
openalex   +1 more source

Experimental diabetes.

Clinical proceedings, 1946
papel
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Les techniques de percussion : un reflet des changements techniques durant l’Acheuléen

Archéopages, 2021
Sophie Clément
doaj   +1 more source

Adaptive experimentation and optimization in organic chemistry. [PDF]

Beilstein J Org Chem
Schweidtmann AM, Schwaller P.
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Tobacco and vaping exposure among Spanish adolescents: An analysis of digital, social, school, and family environments. [PDF]

Tob Induc Dis
Rodrigo CS, Escolar-Llamazares MC, Val EIM, Sáiz-Manzanares MC, Martínez Martín MÁ.   +4 more
europepmc   +1 more source