Results 171 to 180 of about 649,224 (361)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Next generation internet experimentation: drivers transforming next generation internet research and experimentation

open access: yes, 2016
In a world where competitive economies are increasingly dependent on innovative application of information and communication technologies and where changes in technology and culture are happening rapidly, Europe must remain at the forefront of the Next ...

core  

Advanced Chemical Experimentation and Instrumentation

open access: yes, 2023
5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy.
Tokmakoff, Andrei, Gheorghiu, Mircea
core  

The Role of Information in Competitive Experimentation [PDF]

open access: yes
Technological progress is typically a result of trial-and-error research by competing firms. While some research paths lead to the innovation sought, others result in dead ends. Because firms benefit from their competitors working in the wrong direction,
Ufuk Akcigit, Qingmin Liu
core   +2 more sources

Typification of Linaria badalii (Plantaginaceae, Antirrhineae), and the problem of the original material used to describe the species

open access: yesMediterranean Botany
The typification of the name Linaria badalii (Plantaginaceae, Antirrhineae), is discussed. The designation of the nomenclatural type is based on an assessment of Loscos’s original material collected by Antonio Badal in Las Parras de Martín (Teruel ...
Pedro Pablo Ferrer Gallego   +1 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

UNIVERSITY OF MELBOURNE ANIMAL EXPERIMENTATION ETHICS COMMITTEE MINUTES

open access: yes, 1992
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/71250The
University of Melbourne. Animal Experimentation Ethics Committee
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Experimentation to Reduce Friction from Novel Abrasive Tape Polishing Method

open access: yes, 2010
The aim is to develop and improve a finishing process that allows reduced CO2 emissions, through reduced use of carbon-based fuels, achieving improvement in fuel consumption.
Chen, Xun, Blunt, Liam, Wilkinson, Adam
core  

A Case Study in the Philosophy of Scientific Experimentation: Electron-Proton Inelastic Scattering Program in High Energy Particle Physics [PDF]

open access: yes, 2007
In this paper, I address the issue of to what extent the theory-dominated view of scientific experimentation describes scientific practice. I rely on a time period from the history of High Energy Physics (HEP), which spans from early 1960s to early 1970s.
k.karaca@utwente.nl, Koray Karaca
core  

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