Results 111 to 120 of about 11,084,548 (300)

3-D immersive screen experiments [PDF]

, 2010
We are currently piloting a range of computer simulated science experiments as 3-D virtual environments. These are rendered on a PC in 3-D and use photographs of specic parts of the actual apparatus as textures to add realism to the simulation.
Lucas, Robert
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

MIREX: MapReduce Information Retrieval Experiments [PDF]

, 2010
We propose to use MapReduce to quickly test new retrieval approaches on a cluster of machines by sequentially scanning all documents. We present a small case study in which we use a cluster of 15 low cost ma- chines to search a web crawl of 0.5 billion ...
Hauff, Claudia, Hiemstra, Djoerd
core   +6 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Competency Learning by Machine Learning-Based Data Analysis with Electroencephalography Signals

Education Sciences
Data analysis and machine learning have become essential cross-disciplinary skills for engineering students and professionals. Traditionally, these topics are taught through lectures or online courses using pre-existing datasets, which limits the ...
Javier M. Antelis, Myriam Alanis-Espinosa, Omar Mendoza-Montoya, Pedro Cervantes-Lozano, Luis G. Hernandez-Rojas   +4 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Between syntax and morphology: German noun+verb units

Glossa
We show that graphemic variation—at least in some writing systems—can be analysed in terms of grammatical variation given a usage- based probabilistic view of the grammar-graphemics interface.
Roland Schäfer, Ulrike Sayatz
doaj   +2 more sources

Experimenting with a Design Experiment.

Revista internacional de sociologia, 2011
The design experiment is an experimental research method that aims to help design and further develop new (policy) instruments. For the development of a set of guidelines for the facilitation of citizens’ initiatives by local governments, we are experimenting with this method.
Bakker, Judith, Denters, Sebastianus A.H.   +1 more
openaire   +2 more sources

Novel Knowledge: Judgement, Experience, Experiment

XVII-XVIII, 2010
Cet article vise à montrer que le roman de la première moitié du XVIIIe siècle, dans le contexte de la révolution scientifique, est un roman expérimental, quoiqu’il faille concevoir l’expression dans un sens différent de celui qu’entend Zola lorsqu’il affirme que “ le raisonnement expérimental est basé sur le doute.” Quoique le doute demeure une ...
openaire   +2 more sources