Results 201 to 210 of about 3,940,538 (284)

Prompting large language models and evaluating inter- and intra-rater agreement for cancer progression assessment from radiology reports. [PDF]

ESMO Real World Data Digit Oncol
Kristjánsson TÓ, Henriksen AF, Hansen ML, Kovacs DG, Bjerrum A.   +4 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Construction of Nursing Management Protocol for Promoting Tolerance of Enteral Nutrition in Tube-Fed Perioperative Cancer Patients. [PDF]

J Multidiscip Healthc
Wang J, Wang Y, Jia N, Zhang Y, Zhou J, Bao J, Ni R, Zuo W, Li Y, Yang Z.   +9 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

HLA Experts' Perspectives on Precision Medicine and Molecular Matching in Kidney Transplantation: A Qualitative Study. [PDF]

Can J Kidney Health Dis
An L, Affdal A, Ballesteros F, Malo MF, Cochran-Mavrikakis SL, Sancho C, Tousignant N, Bryan S, Keown P, Sapir-Pichhadze R, Fortin MC.   +10 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Comprehensive performance assessment of the BMIA-12 a system for bone marrow cell quantification in normal and hematological malignancy samples. [PDF]

Sci Rep
Kim HN, Lee JH, Jung Y, Kwon JA, Yoon SY.   +4 more
europepmc   +1 more source

Enzymatic and microbial routes to bioplastics: The green chemistry frontier of biopolymers

FEBS Open Bio, EarlyView.
Microbial biosynthesis and engineered enzyme platforms are expanding the design space of polyhydroxyalkanoate bioplastics. By combining fermentation, PHA synthase engineering and cell‐free modular systems, tailored biodegradable polymers can be produced with tunable properties, supporting more sustainable materials and future circular bioeconomy ...
Giovanni Gallo, Emma Piccoli, Luca Bombardi, Martina Aulitto, Salvatore Fusco   +4 more
wiley   +1 more source

Integrating subjective perceptions and objective video analysis to identify challenges in laparoscopic suturing: a cross-sectional study to enhance surgical training. [PDF]

Sci Rep
Ogbonnaya C, Li S, Tang C, Zhang B, Sullivan P, Erden MS, Tang B.   +6 more
europepmc   +1 more source