Results 101 to 110 of about 2,735,740 (399)

Medical 3D printing: methods to standardize terminology and report trends. [PDF]

open access: yes, 2017
BackgroundMedical 3D printing is expanding exponentially, with tremendous potential yet to be realized in nearly all facets of medicine. Unfortunately, multiple informal subdomain-specific isolated terminological 'silos' where disparate terminology is ...
Chepelev, Leonid   +4 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Practice Guideline on Prevention, Diagnosis, and Treatment of Rhino-Orbito-Cerebral Mucormycosis in the COVID-19 Area: A Consensus of Iranian Experts [PDF]

open access: diamond, 2022
Farzad Pakdel   +5 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Assessment of the cortisol awakening response: expert consensus guidelines [PDF]

open access: yes, 2015
The cortisol awakening response (CAR), the marked increase in cortisol secretion over the first 30–45 min after morning awakening, has been related to a wide range of psychosocial, physical and mental health parameters, making it a key variable for ...
Adam, E.K.   +29 more
core   +2 more sources

Management of achalasia cardia: Expert consensus statements [PDF]

open access: yesJournal of Gastroenterology and Hepatology, 2018
AbstractAchalasia cardia (AC) is a frequently encountered motility disorder of the esophagus resulting from an irreversible degeneration of neurons. Treatment modalities are palliative in nature, and there is no curative treatment available for AC as of now. Significant advancements have been made in the management of AC over last decade.
Ramchandani, Mohan   +13 more
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Selection for hepatic resection: expert consensus conference [PDF]

open access: yesHPB, 2013
This consensus conference is timely, as the past decade has witnessed an explosion of patients deemed suitable for resection of colorectal metastases to the liver (CRLM). This is reflected in an increased complexity of surgical procedures in patients with more advanced disease.
Rees, Myrddin   +3 more
openaire   +2 more sources

Consensus Statement by the Expert Advisory Committee

open access: yesКардиоваскулярная терапия и профилактика, 2012
Тема: Место комбинированной гиполипидемической терапии (статин + эзетимиб) в лечении дислипидемий Дата: 09.10.2011 Место проведения: г. Москва Председатели: Президент ВНОК, акад. РАМН Р.Г.
article Editorial
doaj   +1 more source

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