Results 51 to 60 of about 921,712 (312)

Liver imaging reporting and data system: An expert consensus statement [PDF]

, 2017
The increasing incidence and high morbidity and mortality of hepatocellular carcinoma (HCC) have inspired the creation of the Liver Imaging Reporting and Data System (LI-RADS).
Agrons, Michelle M, Bashir, Mustafa R, Chernyak, Victoria, Do, Richard K, Elsayes, Khaled M, Fowler, Kathryn J, Kielar, Ania Z, Mitchell, Donald G, Sirlin, Claude B, Szklaruk, Janio, Tang, An   +10 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The Parliament of the Experts [PDF]

, 2009
In the administrative state, how should expert opinions be aggregated and used? If a panel of experts is unanimous on a question of fact, causation, or prediction, can an administrative agency rationally disagree, and on what grounds?
Vermeule, Adrian
core   +2 more sources

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Guidelines for the management of the foot health problems associated with rheumatoid arthritis [PDF]

, 2011
Background. Rheumatoid arthritis (RA) as a chronic systemic disease, commonly affects the feet, impacting negatively on patients' quality of life. Specialist podiatrists have a prime role to play in the assessment and management of foot and ankle ...
Bowen, C, Dagg, A, Davies, S, Graham, A, Longrigg, K, Lyons, C, Williams, AE   +6 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Consensus Statement by the Expert Advisory Committee

Кардиоваскулярная терапия и профилактика, 2012
Тема: Место комбинированной гиполипидемической терапии (статин + эзетимиб) в лечении дислипидемий Дата: 09.10.2011 Место проведения: г. Москва Председатели: Президент ВНОК, акад. РАМН Р.Г.
article Editorial
doaj   +1 more source

I.S.Mu.L.T. Achilles Tendon Ruptures Guidelines [PDF]

, 2018
This work provides easily accessible guidelines for the diagnosis, treatment and rehabilitation of Achilles tendon ruptures. These guidelines could be considered as recommendations for good clinical practice developed through a process of systematic ...
Alessio Giai Via,, Alfonso Maria Forte,, Angelo De Carli,, Anna, Collina, Antonio, Vadal\ue0, Asmaa, Mahmoud, Bernardi, Gabriele, Bernardo, Innocenti, Biagio, Moretti, Biz, Carlo, Calogero, Foti, Carlotta, Galeone, Clelia, Rugiero, Daniela, Buonocore, Domenico, Lupariello, Edoardo, Gaj, Eleonora, Piccirilli, Emanuela, Marsilio, Fantoni, Ilaria, Finotti, Paolo, Francesca, Veronesi, Francesco Di Pietto,, Frizziero, Antonio, Gamberini, Jacopo, Gasparini, Monica, Imma Di Lanno,, Johnny, Padulo, Leonardo, Pellicciari, Luca, Perazzo, Luigi Di Lorenzo,, Manuela, Verri, Marcello, Zappia, Maria Chiara Vulpiani,, Mario, Vetrano, Matteo, Baldassarri, Maurizia, Dossena, Michela, Bossa, Milena, Fini, Nicola, Maffulli, Oliva, Francesco, Pasquale, Farsetti, Pietro, Picerno, Roberto, Buda, Ruggieri, Pietro, Simone, Natali, Umberto, Tarantino, Vincenzo De Luna,, Vito, Chianca   +47 more
core   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source