Results 71 to 80 of about 1,589,292 (261)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Setting implementation research priorities to reduce preterm births and stillbirths at the community level. [PDF]

, 2011
Asha George and colleagues from the GAPPS group report the implementation research priorities to address prematurity and stillbirths at the community level that resulted from their recent expert consensus ...
Rudan, I, Rubens, C, Young, M, GAPPS Expert Group on Community Based Strategies and Constraints, The, Victora, CG, George, A, Bang, A, Chan, KY, Chopra, M   +8 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Expert consensus on the adjustment of whole blood donation interval for voluntary blood donation

Zhongguo shuxue zazhi
Voluntary blood donation is the cornerstone of safe clinical blood use. In the context of demographic transition and growing healthcare demand, scientifically determining an appropriate whole blood donation interval has become an important strategy for ...
Expert Consensus Writing Group of Adjustment of Whole Blood Donation Interval for Voluntary Blood Donations
doaj   +1 more source

Lasers in melasma: A review with consensus recommendations by Indian pigmentary expert group

Indian Journal of Dermatology, 2017
Lasers have come up as the newest therapeutic modality in dermatological conditions including melasma. In this article, as a group of experts from Pigmentary Disorders Society in collaboration with South Asian Pigmentary Disorders Forum (SPF), we have ...
Rashmi Sarkar, Sanjeev Aurangabadkar, T Salim, Anupam Das, Swapnil Shah, Imran Majid, Mohan Singh, G Ravichandran, Kiran Godse, Shehnaz Arsiwala, Latika Arya, Narendra Gokhale, Nilendu Sarma, R G Torsekar, Sidharth Sonthalia, V K Somani   +15 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Diabetic neuroosteoarthropathy: an interdisciplinary expert consensus

Сахарный диабет
OBJECTIVE. To analyze and describe existing methods for the diagnosis and treatment of diabetic neuroosteoarthropathy.MATERIALS AND METHODS. A search and analysis of clinical trials, meta-analyses, systematic reviews and clinical guidelines on the ...
V. B. Bregovskii, G. Y. Strakhova, S. A. Osnach, V. N. Khramilin, G. R. Galstyan, A. Y. Tokmakova, E. Y. Komelyagina, V. G. Protsko, A. L. Rybinskaya, A. K. Mursalov, G. P. Ivanov, I. A. Pakhomov, V. N. Obolenskii, E. P. Sorokin, V. V. Kuznetsov, S. I. Kireev, I. V. Gur'eva, V. A. Mitish, Y. S. Paskhalova, P. S. Bardyugov   +19 more
doaj   +1 more source

Step-by-step process of developing the expert consensus list of essential antidotes.

, 2022
Step-by-step process of developing the expert consensus list of essential antidotes.
Bedoor Qabazard (481565), Sara Al-Ansari (12883906), Dalal Al-Taweel (7542584), Asmaa Al-Haqan (12883909), Samuel Koshy (5721119)   +4 more
core   +1 more source