Results 111 to 120 of about 2,117,343 (302)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Patient/Family Education for Newly Diagnosed Pediatric Oncology Patients [PDF]
, 2016 There is a paucity of data to support evidence-based practices in the provision of patient/family education in the context of a new childhood cancer diagnosis.
Ahern, JoAnn +20 more
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Evidence, Experts and Systematic Reviews. Has COVID-19 changed their importance?
Journal of Evidence-Based Healthcare, 2021 Ricardo Maia Ferreira
doaj +1 more source
The Role Of Local Authorities In Health Issues: A Policy Document Analysis [PDF]
, 2015 Prior to the passing of the Health and Social Care Act 2012 the Communities and Local Government (CLG) Select Committee conducted an investigation into the proposed changes to the Public Health System in England.
Coleman, A. +3 more
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The Proficiency of Experts [PDF]
, 2018 Expert evidence plays a crucial role in civil and criminal litigation. Changes in the rules concerning expert admissibility, following the Supreme Court\u27s Daubert ruling, strengthened judicial review of the reliability and the validity of an expert ...
Garrett, Brandon L., Mitchell, Gregory
core +2 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
How \u3ci\u3eDaubert\u3c/i\u3e and its Progeny Have Failed Criminalistics Evidence and a Few Things the Judiciary Could Do About It. [PDF]
, 2018 Part I documents how courts have failed to faithfully apply Daubert’s criteria for scientific validity to this type of evidence. It describes how ambiguities and flaws in the terminology adopted in Daubert combinedwith the opaqueness of forensic-science ...
Kaye, David H.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source