Results 61 to 70 of about 579,829 (295)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
, 2021 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.The current paper builds on the naturalistic decision-making paradigm to advance the meaning and ...
Watt, J +5 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Improving Access to Justice for Women Who Kill Their Abusers: Practitioner Insights and Experiences
International Journal for Crime, Justice and Social DemocracyOver the past decade, Australia has made significant reforms aimed at improving legal understandings of intimate partner violence, women’s use of force and their access to self-defence. While some courts have recognised the cumulative effects of coercive
Danielle Tyson +2 more
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Comment: The standards in admitting expert evidence in Ethiopia: some practical discrepancies
Mizan Law Review, 2017 Judges render justice based on the presented evidence justifying their decisions. In criminal cases, these decisions can have ramifications on an individual’s right to liberty, life and property.
Abreha Mesele Zinabu
doaj +1 more source
Expert evidence in criminal proceedings [PDF]
, 2020 1 Expert evidence in criminal proceedings Abstract Rigorosum thesis addresses expert evidence in criminal proceedings. For more than a century, experts are being taken on the criminal proceedings to clarify technical facts to law enforcement or judicial ...
Šimková, Radka
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Wisconsin attorneys in selection of vocational expert witnesses [PDF]
, 1999 Plan BThe purpose of this descriptive study is to rank order the vocational characteristic competencies, as perceived by Wisconsin attorneys that specialized in Workers’ Compensation cases, when selecting a vocational expert.
Ong, Lee Za
core