Results 91 to 100 of about 1,385,906 (244)

Atom Probe Tomography as an Emerging Tool for Understanding Defect‑Driven Mechanisms in HfO2‑Based Ferroelectrics

open access: yesAdvanced Functional Materials, EarlyView.
This Perspective highlights atom probe tomography as a powerful tool for understanding the atomic‐scale defect chemistry in HfO2‐based ferroelectrics. 3D mapping of dopants, point defects, and interface chemistry can provide new insight into defect‐driven mechanisms underpinning the ferroelectricity in the system and guide the design of more reliable ...
Kasper Hunnestad   +3 more
wiley   +1 more source

The influence of professionals’ personal views and values in the development of guidelines for rare diseases: an example from phenylketonuria

open access: yesOrphanet Journal of Rare Diseases
Background In the process of guideline development, expert opinion is introduced when there is low-quality or no scientific evidence available. During the first revision of the European phenylketonuria guidelines, the limited data regarding adult ...
Annemiek M. J. van Wegberg   +2 more
doaj   +1 more source

An expert opinion: upper limb rehabilitation after stroke

open access: yesAdvances in Clinical Neuroscience & Rehabilitation, 2019
Somewhere between 50-80% of stroke survivors have upper limb symptoms after acute stroke1 and persistent difficulty in using the upper limb is a major contributor to ongoing physical disability.2 A commonly held view is that most recovery from stroke ...
Nick Ward, Kate Kelly, Fran Brander
doaj   +1 more source

Targeting Autophagy In Disease: Recent Advances In Drug Discovery

open access: yes, 2020
Introduction Small molecules targeting autophagy have been highly implicated as new therapeutic agents to treat diseases of interest. With the increasing demand for autophagy-targeting drugs, this review attempts to provide an efficient strategy to ...

core   +1 more source

Load Distributing Metamaterials Via Discrete Optimization

open access: yesAdvanced Functional Materials, EarlyView.
Mechanical metamaterials are computationally optimized to homogenize transmitted forces by minimizing the spread of reaction forces. The resulting architectures transform localized loading into broader, more uniform force distributions and experimentally demonstrate robust load spreading under quasi‐static and impact loading.
Andrea Detry   +6 more
wiley   +1 more source

Treating epileptic emergencies - pharmacological advances

open access: yes, 2016
Introduction: Epileptic emergencies are frequently encountered and include ictal events as status epilepticus or seizure clusters, and non-ictal situations like postictal psychosis or acute drug side effects. The aim of this review was to describe recent
Ben-Menachem, Elinor,, Zelano, Johan,
core   +1 more source

Nutritional intervention in chronic pain : innovative way of targeting central nervous system sensitization?

open access: yes, 2020
Introduction Few treatment programs for chronic pain nowadays take a dietary pattern or adipose status into account. Areas covered An important role of neuroinflammation in chronic pain is now well established, at least in part due to increased central ...
Van Oudenhove, Lukas   +25 more
core   +1 more source

Sacrificial‐Layer‐Assisted Heat‐Affected‐Zone Suppression in Laser Patterning of PET for High‐Performance Flexible Devices

open access: yesAdvanced Functional Materials, EarlyView.
A removable sacrificial polymer layer engineers the thermal boundary condition during nanosecond laser ablation of PET, suppressing heat‐affected‐zone formation without relying on costly ultrafast lasers. This strategy enables deep, high‐aspect‐ratio trenches with no detectable heat‐affected zone, templating silver‐filled mesh electrodes with record ...
Mehdi Zarei   +3 more
wiley   +1 more source

An update on inclisiran for the treatment of elevated LDL cholesterol

open access: yes
Introduction The burden of atherosclerotic cardiovascular disease (ASCVD) persists globally, demanding innovative therapeutic strategies. This manuscript provides an expert opinion on the significance of managing low-density lipoprotein cholesterol in ...
Ray, Kausik, Barkas, Fotios
core   +1 more source

Modeling Without Data Using Expert Opinion [PDF]

open access: yes, 2009
The expert package provides tools to create and manipulate empirical statistical models using expert opinion (or judgment). Here, the latter expression refers to a specific body of techniques to elicit the distribution of a random variable when data is ...
Goulet, Vincent   +2 more
core  

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