Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Multimodal Migraine Management and the Pursuit of Migraine Freedom: A Narrative Review
Neurology and Therapy, 2023 Migraine is a neurologic disease with a complex pathophysiology that can be controlled with current treatment options but not cured. Therefore, treatment expectations are highly variable.
Andrew M. Blumenfeld +7 more
doaj +1 more source
Landscape character in the expert opinions typology of forensic ecotechnique: forest and trees [PDF]
, 2014 The paper deals with the issue of landscape character within the expert opinions typology of Forensic ecotechnique: forest and trees. Expert opinions regarding landscape character are classified according to the character of task.
Honzová, Markéta
core
Expert opinions and scientific evidence for colonoscopy key performance indicators
Gut, 2016 Colonoscopy is a widely performed procedure with procedural volumes increasing annually throughout the world. Many procedures are now performed as part of colorectal cancer screening programmes.
C. Rees +12 more
semanticscholar +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
Вестник Дагестанского государственного технического университета: Технические науки, 2023 Objective. The aim of the study is to develop an effective express method for the formation of a representative expert coalition based on the analysis of correlations between expert opinions.Method.
R. A. Zhilin
doaj +1 more source
Improving visual attractiveness to enhance city-river integration - a methodological approach for ongoing evaluation [PDF]
, 2012 The relationship between rivers and cities has evolved from a natural coexistence and interdependence to a progressive relationship of segregation and disintegration.
Bernardo, Fátima +3 more
core +2 more sources
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Exploring high-end climate change scenarios for flood protection of the Netherlands [PDF]
, 2009 This international scientific assessment has been carried out at the request of the Dutch Delta Committee. The "Deltacommissie" requested that the assessment explore the high-end climate change scenarios for flood protection of the Netherlands.
Beersma, J.J. +19 more
core +1 more source
Expert Opinions on Improving Femicide Data Collection across Europe: A Concept Mapping Study
PLoS ONE, 2016 Femicide, defined as the killings of females by males because they are females, is becoming recognized worldwide as an important ongoing manifestation of gender inequality.
C. Vives‐Cases +7 more
semanticscholar +1 more source