Results 151 to 160 of about 480,826 (310)

2025 Canadian Urological Association Expert Report: Muscle-invasive bladder cancer. [PDF]

Can Urol Assoc J
Kulkarni GS, Black PC, Sridhar SS, Zlotta AR, Shayegan B, Rendon RA, Chung P, van der Kwast T, Alimohamed N, Fradet Y, Kokorovic A, Cury FL, Kassouf W, Bossé D, Izard J, McAlpine K.   +15 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

MIBC Expert Report: A comprehensive, multidisciplinary roadmap for navigating a rapidly evolving therapeutic landscape. [PDF]

Can Urol Assoc J
Bossé D.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Exploring mock juror evaluations of forensic evidence conclusion formats within a complete expert report. [PDF]

Forensic Sci Int Synerg
Bali AS, Martire KA.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

2024 CUA-GUMOC Expert Report: Management of unresectable locally advanced and metastatic urothelial carcinoma. [PDF]

Can Urol Assoc J
Stecca CE, Chowdhury D, Blais N, Alimohamed N, Wood L, Canil CM, Eigl B, Kulkarni GS, Black PC, Kassouf W, Chung P, North S, Jiang DM, Sridhar SS.   +13 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

WHO Expert Committee on Drug Dependence, Thirty-fourth report.

, 2006
The WHO Expert Committee on Drug Dependence met in Geneva from 28 to 31 March 2006. Dr Howard Zucker, Assistant Director-General, Health Technology and Pharmaceuticals, and Dr Hans Hogerzeil, Director of Medicines Policy and Standards, welcomed the ...

core  

2024 CUA-KCRNC Expert Report: Management of non-clear cell renal cell carcinoma. [PDF]

Can Urol Assoc J
Graham J, Ahmad AE, Basappa NS, Bernhard JC, Bhindi B, Bossé D, Breau RH, Canil CM, Castonguay V, Finelli A, Heng DYC, Inman BA, Kollmannsberger C, Lalani AA, Lavallée LT, Msaouel P, Prendeville S, Soleimani M, Tanguay S, Wood L, Richard PO.   +20 more
europepmc   +1 more source