Results 101 to 110 of about 23,690,640 (370)
On the Plausibility and Scope of Expert Systems in Management [PDF]
Vasant Dhar
openalex +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
An expert system for mitigation actions
This paper describes an approach, based on ontologies and expert system technology, for assisting the mitigation of advanced persistent threat (APT) attacks against critical infrastructures. We describe the approach, and a prototype expert system based on it.
Karanta, Ilkka, Rautila, Mika
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Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien+7 more
wiley +1 more source
An Expert is Worth One Token: Synergizing Multiple Expert LLMs as Generalist via Expert Token Routing [PDF]
We present Expert-Token-Routing, a unified generalist framework that facilitates seamless integration of multiple expert LLMs. Our framework represents expert LLMs as special expert tokens within the vocabulary of a meta LLM. The meta LLM can route to an expert LLM like generating new tokens. Expert-Token-Routing not only supports learning the implicit
arxiv
A field investigation of the effects of expert systems use on the information processing capacity of the organization [PDF]
John J. Sviokla
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Inks, drilling fluids, shower gels and drug delivery vehicles are just a few examples of the many industrial and consumer products based on colloidal and nanostructured complex fluids. The successful formulation of these materials is promoted by understanding how rheological behaviour, which typically dictates performance, relates to underlying ...
S.P. Carrington, Samiul Amin
openaire +2 more sources
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Design of an emergency medical information system for mass gatherings
Background: The frequency of mass gatherings is increasing. Such events often involve many people and carry the risk of mass casualty incidents, which require substantial medical resources from various healthcare institutions. The current medical system,
Yu Tian+6 more
doaj
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source