Results 141 to 150 of about 23,690,640 (370)
Enhanced Maintenance and Explanation of Expert Systems Through Explicit Models of Their Development [PDF]
, 1985 Robert Neches +2 more
openalex +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
FEBS Open Bio, EarlyView.We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo +2 more
wiley +1 more source
Embedding expert knowledge and hypothetical data bases into a data base system [PDF]
, 1980 Michael Stonebraker, Kenneth H. Keller
openalex +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
FEBS Open Bio, EarlyView.A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
wiley +1 more source
Proposal of neural network model for neurocognitive rehabilitation and its comparison with fuzzy expert system model. [PDF]
BMC Med Inform Decis Mak, 2023 Kotyrba M +7 more
europepmc +1 more source
Expert systems tools for hubble space telescope observation scheduling [PDF]
, 1987 G. E. Miller +3 more
openalex +1 more source
Second Generation Expert Systems
Future Generation Computer Systems, 1985 Second generation expert systems are able to combine heuristic reasoning based on rules, with deep reasoning based on a model of the problem domain. This solves a number of major problems of current expert systems, most importantly the problem of knowledge acquisition: second generation expert systems can learn new rules by examining the results of ...
openaire +5 more sources
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
The frame-definition language for customizing the Raffaello structure-editor in host expert systems [PDF]
, 1986 Ephraim Nissan
openalex +1 more source
FEBS Open Bio, EarlyView.We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei +6 more
wiley +1 more source