Results 171 to 180 of about 25,120,416 (357)

Structural and functional analysis of Bacillus sarcosine oxidase and its activity toward cyclic imino acids

open access: yesFEBS Open Bio, EarlyView.
Sarcosine oxidase from Bacillus sp. (SoxB) recognizes l‐proline (l‐Pro), d‐proline (d‐Pro), and l‐thioproline (l‐Tpr) as minor substrates. In this study, we measured their absorption spectra, determined the crystal structures of their enzyme complexes, and performed site‐directed mutagenesis of key residues.
Yuqi Zhang   +5 more
wiley   +1 more source

Expert system applications in customer service [PDF]

open access: bronze, 1989
Stephen Schon, Omar Keith Helferich
openalex   +1 more source

Expert Systems With Applications

open access: yesSocial Science Research Network
Som Gupta
semanticscholar   +1 more source

Expert system verification concerns in an operations environment [PDF]

open access: yes
The Space Shuttle community is currently developing a number of knowledge-based tools, primarily expert systems, to support Space Shuttle operations. It is proposed that anticipating and responding to the requirements of the operations environment will ...
Goodwin, Mary Ann, Robertson, Charles C.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Distributed systems status and control [PDF]

open access: yes
Concepts are investigated for an automated status and control system for a distributed processing environment. System characteristics, data requirements for health assessment, data acquisition methods, system diagnosis methods and control methods were ...
Kreidler, David, Vickers, David
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

An evaluation of selected (Q)SARs/expert systems for predicting skin sensitisation potential. [PDF]

open access: yesSAR QSAR Environ Res, 2018
Fitzpatrick JM, Roberts DW, Patlewicz G.
europepmc   +1 more source

Reliability and performance evaluation of systems containing embedded rule-based expert systems [PDF]

open access: yes
A method for evaluating the reliability of real-time systems containing embedded rule-based expert systems is proposed and investigated. It is a three stage technique that addresses the impact of knowledge-base uncertainties on the performance of expert ...
Adams, Milton B.   +2 more
core   +1 more source

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