Results 61 to 70 of about 27,795,417 (374)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Comprehensive dataset of Portuguese folk instruments for computer vision and heritage researchMendeley Data

open access: yesData in Brief
This dataset contains visual data of traditional Portuguese musical instruments extracted from videos available on the “A Música Portuguesa A Gostar Dela Própria” webpage. This cultural and musical documentation platform provides an authentic perspective
Luis Augusto Silva Zendron   +4 more
doaj   +1 more source

An hierarchical approach to performance evaluation of expert systems [PDF]

open access: yes
The number and size of expert systems is growing rapidly. Formal evaluation of these systems - which is not performed for many systems - increases the acceptability by the user community and hence their success.
Dominick, Wayne D., Kavi, Srinu
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

PCLIPS: Parallel CLIPS [PDF]

open access: yes
PCLIPS (Parallel CLIPS) is a set of extensions to the C Language Integrated Production System (CLIPS) expert system language. PCLIPS is intended to provide an environment for the development of more complex, extensive expert systems.
Gryphon, Coranth D., Miller, Mark D.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A Comparative Study of In Situ Methodologies for Assessment of RF EMF Exposure From a 5G FR2 Base Station

open access: yesIEEE Access
In this work, in situ measurements of the radio frequency electromagnetic field exposure have been conducted for an indoor massive MIMO 5G base station operating at 26–28 GHz.
Samuel Goegebeur   +9 more
doaj   +1 more source

Real-time diagnostic expert systems

open access: yesComputer Assisted Methods in Engineering and Science, 2023
The aim of the paper is to point out the most important factors that should be taken into account during the designing of expert systems for technical diagnostics and advanced condition monitoring.
Wojciech Cholewa
doaj  

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