Results 71 to 80 of about 27,795,417 (374)

Expert systems for superalloy studies [PDF]

open access: yes
There are many areas in science and engineering which require knowledge of an extremely complex foundation of experimental results in order to design methodologies for developing new materials or products. Superalloys are an area which fit well into this
Kaukler, William F., Workman, Gary L.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Review of Orthodontic Expert Systems

open access: yesTurkish Journal of Orthodontics, 2007
The aim of the current study was to introduce a review on orthodontic expert systems. Particularly, in the recent years there is an increase in digital technology to be involved in all scientific fields and it is obvious that orthodontics can not be ...
M. Okan Akçam
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Expert systems built by the Expert: An evaluation of OPS5 [PDF]

open access: yes
Two expert systems were written in OPS5 by the expert, a Ph.D. astronomer with no prior experience in artificial intelligence or expert systems, without the use of a knowledge engineer.
Jackson, Robert
core   +1 more source

Expert systems and finite element structural analysis - a review [PDF]

open access: yes, 1992
Finite element analysis of many engineering systems is practised more as an art than as a science . It involves high level expertise (analytical as well as heuristic) regarding problem modelling (e .g.
Naganarayana, BP, Prathap, Gangan
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Understanding expert systems applications from a knowledge transfer perspective [PDF]

open access: yes, 2009
Expert systems (ESs) were introduced more than two decades ago, but their effectiveness and success are still in debate. This paper attempts to make a contribution to the better understanding of ES applications from a knowledge transfer perspective. This
Duan, Yanqing   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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