Results 71 to 80 of about 325,750 (297)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Dangers of Convictions Based on a Single Piece of Forensic Evidence
Potchefstroom Electronic Law Journal, 2020 The overall goal of the criminal justice system is to ensure that perpetrators of crimes are duly punished and that victims of crimes are duly exonerated.
Adebola Olufunmi Olaborede +1 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The Expert Witness: Lessons from the U.S. Experience
Humana.Mente: Journal of Philosophical Studies, 2015 The first section of this paper explains why assessing the worth of expert testimony poses special epistemological difficulties. The second traces the history of the various rules and procedures by means of which the U.S. legal system has tried to ensure,
Susan Haack
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Relevance of An Expert Witness Report Submitted as Evidence in a Case
Теория и практика судебной экспертизы, 2017 The expert witness report plays a crucial part in any type of forensic investigation; forensic engineering and land surveying are no exception. This article focuses on relevance as a major criterion in the evaluation of a forensic expert’s report.
Z. V. Trifonova
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Civil Justice Systems in Europe and the United States [PDF]
, 2002 Professor Dr. Hein D. Kötz - dean of Bucerius Law School in Hamburg, Germany, and a leading scholar in comparative law - presents the inaugural Herbert L.
Kötz, Hein
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source